Evidence map›Paper›PMID 41511367›Full record

ReviewCells2026

MicroRNAs in Prostate Cancer Liquid Biopsies: Early Detection, Prognosis, and Treatment Monitoring.

Seyyed Mohammad Yaghoubi, Erfan Zare, Sina Jafari Dargahlou, Maryam Jafari, Mahdiye Azimi, Maedeh Khoshnazar, Solmaz Shirjang, Behzad Mansoori

Abstract readReview
In one paragraph

Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seyyed Mohammad YaghoubiDepartment of Plant, Cell and Molecular Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz 5166616471, Iran.ORCID 0009-0006-3423-5336
Erfan ZareCancer Immunology and Immunotherapy Research Center, Ardabil University of Medical Sciences, Ardabil 5371713111, Iran.ORCID 0000-0001-7899-8593
Sina Jafari DargahlouDepartment of Biophysics, Faculty of Advanced Technologies, University of Mohaghegh Ardabili, Namin 5619911367, Iran.
Maryam JafariStudent Research Committee, School of Medicine, Anzali International Campus, Guilan University of Medical Sciences, Rasht 4144666949, Iran.
Mahdiye AzimiPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz 5165665811, Iran.
Maedeh KhoshnazarDepartment of Developmental Biology, TeMS.C. Islamic Azad University, Tehran 1916893813, Iran.ORCID 0009-0002-3168-7709
Solmaz ShirjangGenetics, Genomics and Cancer Biology Program, Sidney Kimmel Comprehensive Cancer Center, Jefferson College of Life Sciences, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Behzad MansooriProgram in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA 19104, USA.ORCID 0000-0001-9444-7134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is a common malignancy in men worldwide, with incidence projected to rise in the coming years. Traditional screening and diagnostic methods, such as prostate-specific antigen (PSA) testing and biopsy, face limitations in specificity and invasiveness. Circulating microRNAs (miRNAs) have emerged as stable, non-invasive biomarkers obtainable via liquid biopsies (blood, urine, semen) that could transform PCa management. These small regulatory RNAs reflect underlying tumor biology and are detectable at early disease stages, enabling improved early detection when used alongside or in place of PSA. Distinct miRNA expression patterns correlate with tumor aggressiveness. For example,

Indexed as

Early Detection of CancerMicroRNAsProstatic NeoplasmsBiomarkers, TumorCirculating MicroRNAHumansLiquid BiopsyMalePrognosisBiomarkers, TumorCirculating MicroRNAMicroRNAsbiomarkersearly detectionliquid biopsiesmicroRNAprognosisprostate cancertreatment monitoring

Identifiers

PMID41511367
PMCPMC12785260

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.