Evidence map›Paper›PMID 41511468›Full record

ArticleeLife2026

Two classes of amine/glutamate multi-transmitter neurons innervate Drosophila internal male reproductive organs.

Marta Chaverra, John Paul Toney, Lizetta D Dardenne-Ankringa, Jace Tolleson Knee, Ann R Morris, Joseph B Wadhams, Sarah J Certel, R Steven Stowers

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Marta ChaverraMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.
John Paul ToneyMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.
Lizetta D Dardenne-AnkringaMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.
Jace Tolleson KneeMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.
Ann R MorrisMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.
Joseph B WadhamsMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.
Sarah J CertelThe University of Montana, Division of Biological Sciences, Bozeman, United States.
R Steven StowersMontana State University, Department of Microbiology and Cell Biology, Bozeman, United States.ORCID https://orcid.org/0000-0002-1473-2478

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK, THOMAS KAUFMAN · 2014 to 2026
$13.5M
Functional role of dual neurotransmitter usage in aggressionR01GM115510 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Sarah J Certel, Karla R. Kaun · 2015 to 2026
$3.1M
NIGMS NIH HHS R01 GM115510NIH HHS 2R01GM115510NIH HHS P40 OD018537
6 · The paper itself

Abstract

The essential outcome of a successful mating is the transfer of genetic material from males to females in sexually reproducing animals from insects to mammals. In males, this culminates in ejaculation, a precisely timed sequence of organ contractions driven by the concerted activity of interneurons, sensory neurons, and motor neurons. Although central command circuits that trigger copulation have been mapped, the motor architecture and the chemical logic that couple specific neuronal subclasses to organ-specific contractility, seminal fluid secretion, and sperm emission remain largely uncharted. This gap in knowledge limits our ability to explain how neural circuits adapt to varying contexts and how their failure contributes to infertility. Here, we present an in-depth anatomical and functional analysis of the motor neurons that innervate the internal male reproductive tract of

Indexed as

Drosophila melanogasterGenitalia, MaleGlutamic AcidMotor NeuronsNeurotransmitter AgentsAnimalsMaleOctopamineSerotoninGlutamic AcidNeurotransmitter AgentsOctopamineSerotoninD. melanogasterejaculationmale fertilityneuronneuroscienceneurotransmitter receptor

Identifiers

PMID41511468
PMCPMC12788803

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.