ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
The role of systemic inflammation in patients with conjunctivochalasis.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare systemic inflammation parameters and blood lipid profile in patients with conjunctivochalasis versus healthy individuals.
methodsThirty patients with conjunctivochalasis(Cch) and thirty age-matched healthy controls were included in this retrospective study. Complete blood count (CBC) parameters and serum levels of total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) were obtained from electronic medical records. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-to-HDL ratio (MHR) were calculated for each participant. Group differences were analyzed statistically.
resultsThe monocyte-to-HDL ratio was significantly higher in the conjunctivochalasis group (p = 0.023), while hemoglobin levels were significantly lower (p = 0.001). No additional significant differences were observed in other hematological or lipid parameters.
conclusionThis study is the first to demonstrate an elevated monocyte-to-HDL ratio in patients with conjunctivochalasis. The concurrent reduction in hemoglobin levels provides further support for a potential systemic association. These findings suggest that conjunctivochalasis may involve not only localized ocular changes but also systemic inflammatory processes.
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