Evidence map›Paper›PMID 41511650›Full record

ReviewClinical & experimental metastasis2026

KIF14 in cancer biology: implications for diagnosis and therapy.

Ashok Kumar Bishoyi, Shaker Al-Hasnaawei, Subbulakshmi Ganesan, Aman Shankhyan, Anima Nanda, Aashna Sinha, Subhashree Ray, Deepak Nathiya

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & experimental metastasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashok Kumar BishoyiDepartment of Microbiology, Faculty of Science, Marwadi University Research Center, Marwadi University, Rajkot, Gujarat, India. ashokkumarbishoyi2@gmail.com.
Shaker Al-HasnaaweiCollege of Pharmacy, the Islamic University, Najaf, Iraq.
Subbulakshmi GanesanDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
Aman ShankhyanSharda School of Pharmacy, Sharda University, Greater Noida, UP, India.
Anima NandaDepartment of Biomedical, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.
Aashna SinhaSchool of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India.
Subhashree RayDepartment of Biochemistry IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, 751003, India.
Deepak NathiyaDepartment of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University Rajasthan, Jaipur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinesin family member 14 (KIF14), a microtubule-associated motor protein, plays a crucial role in cytoskeletal dynamics, intracellular transport, and cell division. Oncological studies have consistently reported KIF14 overexpression across various cancers, including breast, ovarian, lung, liver, and brain tumors, associating it with poor clinical outcomes, increased tumor aggressiveness, and resistance to conventional therapies. This review comprehensively analyzed the involvement of KIF14 in cancer progression, particularly its roles in cell cycle regulation, mitotic spindle formation, and oncogenic signaling pathways. Additionally, the molecular mechanisms underlying its tumorigenic effects, its potential as a prognostic biomarker, and its viability as a therapeutic target are explored. The expanding understanding of KIF14's oncogenic functions present promising opportunities for developing novel therapeutic strategies aimed at this key regulator of tumor growth and metastasis, addressing the urgent need for treatments targeting aggressive and therapy-resistant malignancies.

Indexed as

Biomarkers, TumorKinesinsNeoplasmsOncogene ProteinsAnimalsHumansPrognosisSignal TransductionBiomarkers, TumorKIF14 protein, humanKinesinsOncogene ProteinsCancerKIF14Kinesin superfamilyMotor proteinsOncogene

Identifiers

PMID41511650

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.