Evidence map›Paper›PMID 41512026›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Neural substrate of conditioned stimulus for associative learning in the hippocampus.

Kyogo S Kobayashi, Ren Sogabe, Tsuyoshi Tatsukawa, Jun-Nosuke Teramae, Naoki Matsuo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyogo S KobayashiDepartment of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan.ORCID 0000-0002-2769-9646
Ren SogabeDepartment of Biological Sciences, Graduate School of Systems Life Sciences, Kyushu University, Fukuoka 819-0395, Japan.
Tsuyoshi TatsukawaNonlinear Physics Division, Graduate School of Informatics, Kyoto University, Kyoto 606-8501, Japan.ORCID 0009-0000-4500-6324
Jun-Nosuke TeramaeNonlinear Physics Division, Graduate School of Informatics, Kyoto University, Kyoto 606-8501, Japan.ORCID 0000-0003-3255-0253
Naoki MatsuoDepartment of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan.ORCID 0000-0003-0988-4706

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 25K02312MEXT | Japan Society for the Promotion of Science (JSPS) JP18H02543MEXT | Japan Society for the Promotion of Science (JSPS) JP20K15932MEXT | Japan Society for the Promotion of Science (JSPS) JP21H02597MEXT | Japan Society for the Promotion of Science (JSPS) JP24K02064MEXT | Japan Society for the Promotion of Science (JSPS) JP25115003
6 · The paper itself

Abstract

Associative learning allows animals to learn the predictive relationships between events. Presentation of a conditioned stimulus (CS) preceding an unconditioned stimulus (US) within a short interval associates these events. However, little is known about the neural substrates that represent CSs. By combining in vivo calcium imaging with retrospective identification of dorsal hippocampal CA1 neurons, in which

Indexed as

Association LearningCA1 Region, HippocampalConditioning, ClassicalHippocampusNeuronsAnimalsCalciumFearMaleMemoryMiceMice, Inbred C57BLOptogeneticsProto-Oncogene Proteins c-fosCalciumProto-Oncogene Proteins c-foscalcium imagingc-foscontextual fear conditioningengram cellhippocampus

Identifiers

PMID41512026
PMCPMC12799160

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.