Evidence mapPaperPMID 41514130Full record

ArticleSurgical endoscopy2026

National trend and impact of compensated cirrhosis in patients who underwent metabolic and bariatric surgery: a Nationwide Readmissions Database study.

Ali Esparham, Stephen Phillippe, Zhamak Khorgami

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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3 authors.

Ali EsparhamMashhad University of Medical Sciences, Mashhad, Iran.
Stephen PhillippeDepartment of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, USA.
Zhamak KhorgamiDepartment of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, USA. Zhamak-khorgami@ou.edu.ORCID http://orcid.org/0000-0001-6144-691X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is still a lack of sufficient data regarding the trend of cirrhosis and its impact on the perioperative and postoperative outcomes, and healthcare resource utilization in patients who underwent metabolic and bariatric surgery (MBS). Therefore, our study aimed to examine the impact of cirrhosis on MBS outcomes.

methodsThe current study used the Nationwide Readmissions Database (NRD) 2016-2020. Patients who underwent MBS were divided into cirrhosis and non-cirrhosis groups. Patients younger than 18 years, those with a history of upper gastrointestinal malignancy, and patients with decompensated cirrhosis (portal hypertension, ascites, or varices) and individuals with a previous history of MBS were excluded.

resultsThe cirrhosis and non-cirrhosis groups consisted of 3064 and 538,329 patients, respectively. There was no significant change in the cirrhosis trend in patients who underwent MBS from 2016 to 2020. Cirrhosis was not associated with higher rates of in-hospital mortality (< 11 (< 0.36%) vs 99 (0.02%), p = 0.140), 90-day readmission (180 (6.57%) vs 24,204 (5.01%), p = 0.453), or most major complications. Although the overall incidence was low, cirrhosis was linked to higher rates of hepatic encephalopathy and acute heart failure. Patients with cirrhosis also had longer hospital stays, higher costs, and were more likely to have a non-home discharge. Among patients with cirrhosis, Roux-en-Y gastric bypass (OR 1.63, 95% CI 1.18-2.25, p = 0.003) and duodenal switch (OR 3.54, 95% CI 1.42-8.85, p = 0.007) were associated with a higher readmission rates compared to sleeve gastrectomy.

conclusionThese results may indicate the safety of MBS in patients with compensated cirrhosis and obesity.

Indexed as

Bariatric SurgeryLiver CirrhosisObesity, MorbidPostoperative ComplicationsAdultDatabases, FactualFemaleHeart FailureHepatic EncephalopathyHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedPatient Acceptance of Health CareBariatricChronic liver diseaseCirrhosisMetabolic dysfunction-associated steatotic liver diseaseNationwide Readmissions DatabaseNon-alcoholic steatohepatitis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.