A Tissue Renewal-Based Mechanism Drives Colon Tumorigenesis.

Ryan M Boman, Gilberto Schleiniger, Christopher Raymond, Juan Palazzo, Anne Shehab, Bruce M Boman

Abstract read

In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan M BomanDepartment of Engineering, Drexel University, Philadelphia, PA 19104, USA.

Gilberto SchleinigerCenter for Applications of Mathematics in Medicine, Department of Mathematical Sciences, University of Delaware, Newark, DE 19716, USA.

Christopher RaymondDepartment of Mathematical Sciences, University of Delaware, Newark, DE 19716, USA.

Juan PalazzoDepartment of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Anne ShehabCATX Inc., Princeton, NJ 08542, USA.

Bruce M BomanCenter for Applications of Mathematics in Medicine, Department of Mathematical Sciences, University of Delaware, Newark, DE 19716, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our Goal is to identify how colorectal cancer (CRC) arises in the single-layered cell epithelium (simple columnar epithelium) that lines the luminal surface of the large intestine.

Indexed as

APC genecolorectal cancerfamilial adenomatous polyposissystems biologytissue renewal

Identifiers

PMID41514557

DOI10.3390/cancers18010044

PMCPMC12784660

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.