Evidence mapPaperPMID 41514621Full record

ArticleCancers2025

Post-Operative Complications Do Not Influence Time to Adjuvant Treatment in Breast Cancer Patients Undergoing Implant-Based Reconstructions: Pre-Pectoral Versus Sub-Pectoral.

Gianluca Vanni, Marco Pellicciaro, Marco Materazzo, Alice Bertolo, Amir Sadri, Elisa Campanella, Denisa Eskiu, Ilaria Portarena, Benedetto Longo, Valerio Cervelli and 1 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gianluca VanniBreast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0002-3006-5855
Marco PellicciaroBreast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0001-9557-2850
Marco MaterazzoBreast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0002-3599-061X
Alice BertoloBreast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy.ORCID 0009-0002-6920-360X
Amir SadriPlastic Surgery, Great Ormond Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.ORCID 0000-0002-6084-2950
Elisa CampanellaBreast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy.
Denisa EskiuFaculty of Medicine, Università Cattolica Nostra Signora Del Buon Consiglio, 1001 Tirana, Albania.ORCID 0009-0003-2333-4441
Ilaria PortarenaDepartment of Oncology, Tor Vergata Hospital, 00133 Rome, Italy.
Benedetto LongoPlastic and Reconstructive Surgery, Department of Surgical Science, Tor Vergata University, 00133 Rome, Italy.
Valerio CervelliPlastic and Reconstructive Surgery, Department of Surgical Science, Tor Vergata University, 00133 Rome, Italy.
Oreste Claudio BuonomoBreast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmediate breast reconstruction after mastectomy has progressively shifted toward less invasive approaches. The pre-pectoral approach, avoiding muscle dissection, may reduce post-operative pain, surgical trauma, and recovery time. However, concerns regarding surgical complications and their potential impact on the timing of adjuvant treatments still persist.

methodsA retrospective monocentric study was conducted, including all patients who underwent mastectomy with implant-based breast reconstruction at the Breast Unit of Policlinico Tor Vergata in Rome between January 2014 and March 2024. Patients were classified according to the reconstructive technique as either pre-pectoral or sub-pectoral. Demographic, oncologic, and surgical data were collected and analyzed, with a particular focus on post-operative complications and the timing of adjuvant treatment initiation.

resultsOf 622 patients, 366 (58.9%) underwent sub-pectoral reconstruction and 235 (37.7%) pre-pectoral. Overall, the complication rates were comparable between the two reconstructions (23.8% vs. 20.2%,

Indexed as

breast cancerimplant-based reconstructionpost-operative complicationspre-pectoral breast reconstructiontime to adjuvant treatment

Identifiers

PMID41514621
PMCPMC12784931

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.