Evidence map›Paper›PMID 41514648›Full record

ReviewCancers2025

Chemotherapy for Gastric Cancer Is Not Solely the Domain of the Oncologist.

Gabriel Samasca, Ioana Badiu Tisa, Calin Lazar, Ciprian N Silaghi, Diana Deleanu, Adriana Muntean, Iulia Lupan

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriel SamascaDepartment of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-7645-0716
Ioana Badiu TisaDepartment of Nursing, Iuliu Hatieganu University of Medicine and Pharmacy, 400217 Cluj-Napoca, Romania.
Calin LazarDepartment of Pediatrics 1, Iuliu Hatieganu University of Medicine and Pharmacy, 400370 Cluj-Napoca, Romania.
Ciprian N SilaghiDepartment of Medical Biochemistry, Iuliu Hatieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.ORCID 0000-0003-0212-726X
Diana DeleanuDepartment of Internal Medicine, Regional Institute of Gastroenterology "Prof. Dr. Octavian Fodor", 400162 Cluj-Napoca, Romania.
Adriana MunteanDepartment of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-1724-5915
Iulia LupanDepartment of Molecular Biology, Babes-Bolyai University, 400084 Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse effects of chemotherapeutic agents remain a significant clinical challenge in the management of gastric cancer. Across the literature, discussions of chemotherapy consistently document a range of toxicities, underscoring that even when treatment halts disease progression, it can leave substantial clinical sequelae. Chemotherapy can impact virtually every organ system, producing multiorgan toxicity with meaningful implications for patient quality of life and treatment feasibility. When initiating a new chemotherapy regimen, prior lack of therapeutic benefit is often associated with difficult recovery or inability to tolerate subsequent chemotherapy, thereby constraining future therapeutic options. Given these considerations and the current absence of universally personalized treatment, a multidisciplinary team-comprising a medical oncologist, gastroenterologist, and internist-is essential to the planning and execution of chemotherapy regimens. We recommend that these chemotherapy regimens be administered within internal medicine departments, in collaboration with the medical oncologist and gastroenterologist, because in many cases the adverse effects outweigh the potential benefits of chemotherapy.

Indexed as

a multidisciplinary teamchemotherapygastric cancer

Identifiers

PMID41514648
PMCPMC12784761

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.