Evidence map›Paper›PMID 41514705›Full record

ArticleAnimals : an open access journal from MDPI2025

The Treatment of Contagious Ecthyma in Lambs with a Local Anaesthetic/Antiseptic Wound Formulation Lowers Serum Amyloid A Responses.

Aurora Ortín, Sergio Villanueva-Saz, Delia Lacasta, Peter Andrew Windsor, Antonio Fernández, Pablo Quilez, Hector Ruiz, Alex Gómez, David Guallar, Marta Ruiz de Arcaute

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aurora OrtínAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0002-0313-5926
Sergio Villanueva-SazAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0001-6209-4282
Delia LacastaAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0002-7822-6646
Peter Andrew WindsorSydney School of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia.ORCID 0000-0001-5629-3517
Antonio FernándezAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0002-2557-4890
Pablo QuilezAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0009-0003-9757-3840
Hector RuizAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0002-8474-2831
Alex GómezAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.
David GuallarAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0009-0005-3191-4731
Marta Ruiz de ArcauteAnimal Pathology Department, Veterinary Faculty and Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0002-7655-2472

Funding

Medical Ethics (Australia) and Aragón Government A15_20R and A15_23R (Aragón Government)
6 · The paper itself

Abstract

Contagious ecthyma (CE) is a widespread, highly contagious zoonotic skin disease of small ruminants caused by the Orf virus (ORFV), leading to substantial economic losses and welfare concerns. There is no specific treatment, with topical antiseptics and oral or parenteral antibiotics often administered for preventing secondary infections, risking antimicrobial resistance. This study assessed the effect of treating CE in lambs with an antibiotic-free topical anaesthetic/antiseptic formulation (Tri-Solfen

Indexed as

contagious ecthymalambslocal antiseptic/anaesthetic formulationorf virusserum amyloid A

Identifiers

PMID41514705
PMCPMC12784701

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.