Evidence map›Paper›PMID 41514713›Full record

ArticleAnimals : an open access journal from MDPI2025

iTRAQ-Based Proteomics Reveals the Potential Mechanisms Underlying Diet Supplementation with Stevia Isochlorogenic Acid That Alleviates Immunosuppression in Cyclophosphamide-Treated Broilers.

Jiatong Jin, Shuqi Zhao, Pengyu Zhao, Yushuo Zhang, Lifei Wu, Liangfu Zhou, Yasai Sun, Wen Zhao, Qian Zhou

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiatong JinCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Shuqi ZhaoCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Pengyu ZhaoChen Guang Biotechnology Group Co., Ltd., Handan 057250, China.
Yushuo ZhangCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Lifei WuChen Guang Biotechnology Group Co., Ltd., Handan 057250, China.
Liangfu ZhouCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Yasai SunCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Wen ZhaoCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Qian ZhouCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.

Funding

Hebei Natural Science Foundation C2022204255, C2022204256
6 · The paper itself

Abstract

The extensive use of antibiotics in intensive farming weakens immunity and threatens food safety. Stevia isochlorogenic acid (SICA), a kind of dicaffeoylquinic acid derived from stevia residue, exhibits strong antioxidant activity. This study evaluated the ability of SICA to improve immune function in an immunosuppressed broiler model. SICA significantly increased the spleen, thymus, and bursa of Fabricius indices (

Indexed as

histological examinationimmune organ indicesmolecular docking analysisproteomicsquantitative PCRstevia isochlorogenic acid

Identifiers

PMID41514713
PMCPMC12784939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.