Evidence mapPaperPMID 41514764Full record

ArticleAnimals : an open access journal from MDPI2025

Novel TRIM Proteins Modulating the Innate Immune Response of Rainbow Trout (

Francisco Donoso, Felipe Ramírez-Cepeda, Nicolás Salinas-Parra, Claudio A Álvarez, Paula Santana, Rubén Avendaño-Herrera, Rafael Diego Rosa, Cristian A Valenzuela, Byron Morales-Lange, Luis Mercado

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francisco DonosoDepartment of Anatomy and Neuroscience, APC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.ORCID 0000-0002-7551-6613
Felipe Ramírez-CepedaGrupo de Marcadores Inmunológicos, Laboratorio de Genética e Inmunología Molecular, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340000, Chile.ORCID 0000-0002-5357-3086
Nicolás Salinas-ParraGrupo de Marcadores Inmunológicos, Laboratorio de Genética e Inmunología Molecular, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340000, Chile.ORCID 0000-0001-5278-5928
Claudio A ÁlvarezLaboratorio de Tecnología de Cultivo de Peces Marinos (TECPEMAR), Departamento de Acuicultura, Facultad de Ciencias del Mar, Universidad Católica del Norte, Coquimbo 1780000, Chile.ORCID 0000-0003-3132-2187
Paula SantanaInstituto de Ciencias Aplicadas, Facultad de Ingeniería, Universidad Autónoma de Chile, Santiago 8580640, Chile.ORCID 0000-0002-5742-4926
Rubén Avendaño-HerreraLaboratorio de Patología de Organismos Acuáticos y Biotecnología Acuícola, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Viña del Mar 2340000, Chile.ORCID 0000-0001-5368-4475
Rafael Diego RosaLaBIOMARIS-Laboratory of Biotechnology and Marine Health, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis 88035-972, Brazil.ORCID 0000-0002-4076-3163
Cristian A ValenzuelaGrupo de Marcadores Inmunológicos, Laboratorio de Genética e Inmunología Molecular, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340000, Chile.ORCID 0000-0003-3564-153X
Byron Morales-LangeDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, 1432 Ås, Norway.ORCID 0000-0002-2807-5800
Luis MercadoGrupo de Marcadores Inmunológicos, Laboratorio de Genética e Inmunología Molecular, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340000, Chile.ORCID 0000-0003-3883-5188

Funding

Agencia Nacional de Investigación y Desarrollo FONDECYT 11230658Agencia Nacional de Investigación y Desarrollo FONDECYT 1140797Agencia Nacional de Investigación y Desarrollo FONDECYT 1230712Agencia Nacional de Investigación y Desarrollo FONDECYT 1231088Agencia Nacional de Investigación y Desarrollo FONDECYT 1231206Brazilian National Council for Scientific and Technological Development CNPq; grant no. 304905/2024-0CAPES/COFECUB Program (Sentinels Project; Edital 08/2024 88881.987362/2024-01Centre National de la Recherche Scientifique - CNR EcoHealth4SeaFundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina FAPESC; Edital 21/2024; grant 2024TR002343Interdisciplinary Center for Aquaculture Research INCAR 1523A0007The Research Council of Norway Foods of Norway (RCN 237841/030)The Research Council of Norway ForestFeed project (RCN 344116).
6 · The paper itself

Abstract

In higher vertebrates, Tripartite Motif (TRIM) proteins modulate the immune response by coordinating processes related to inflammation such as antiviral restriction, autophagy and inflammasome activation. In fish, TRIM proteins have been reported mainly in cyprinids (e.g., carp-

Indexed as

fish innate immunologyFlavobacterium psychrophilumLPSOncorhynchus mykissPAMP’s signallingpoly I:CTripartite motif-containing proteins

Identifiers

PMID41514764
PMCPMC12784883

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.