Evidence map›Paper›PMID 41514930›Full record

ArticleBiology2025

GATA-

Layla Al-Mansoori, Asma A Elashi, Laila Hedaya, Maha Alser, Shamma Almuraikhy, Najeha Anwardeen, Hend Al-Jaber, Suhad Hussain, Hamda A Al-Naemi, Vijay Govindharajan and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. AdipocyteCells · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Layla Al-MansooriBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Asma A ElashiBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-6927-5622
Laila HedayaBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-5136-9746
Maha AlserBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3812-1310
Shamma AlmuraikhyBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-4572-9738
Najeha AnwardeenBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-7263-4905
Hend Al-JaberBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-9639-0773
Suhad HussainBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Hamda A Al-NaemiLaboratory Animal Research Centre, Qatar University, Doha P.O. Box 2713, Qatar.
Vijay GovindharajanLaboratory Animal Research Centre, Qatar University, Doha P.O. Box 2713, Qatar.
Rafif Mahmood Al-SaadyCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-7797-9614
Mohammed Imad MalkiCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-6801-2126
Khaled NajaBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-9259-3082
Mohamed A ElrayessBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3803-4604

Funding

Qatar University QPH3P-BRC-2021-604
6 · The paper itself

Abstract

Obesity plays a crucial role in the progression of insulin resistance and type 2 diabetes which are related to inflammation and liver disease. GATA-3 is a transcription factor that is involved in adipogenesis and inflammation. Therefore, it could be a potential therapeutic target for obesity-associated metabolic disorders. This study aimed to examine the effects of GATA-3 suppression on body weight, fat depot redistribution, liver histopathology, and inflammatory markers in transgenic

Indexed as

adipogenesisdb/db miceGATA-3obesitytype 2 diabetes

Identifiers

PMID41514930
PMCPMC12784981

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.