Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.

Han Zheng, Qian Zhang, Qun Liu, Jingjuan Li, Yihui Zhang, Lixia Wang, Jianwei Gao

Abstract readReview

In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Hormone-metabolism crosstalk in plants: an integrated signaling network coordinating growth and stress adaptation.Plant signaling & behavior · 2026
Review
Phytohormonal Regulation of Plant Responses to Major Abiotic Stresses: From Signaling Pathways to Hormonal Crosstalk.Metabolites · 2026
Review
The role of indole acetic acid in modifying morphological features of three Prunus domestica L. cultivars.Scientific reports · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Han ZhengShandong Key Laboratory of Bulk Open-Field Vegetable Breeding, Ministry of Agriculture and Rural Affairs Key Laboratory of Huang Huai Protected Horticulture Engineering, Institute of Vegetables, Shandong Academy of Agricultural Sciences, Jinan 250100, China.ORCID 0000-0002-0111-1453

Qian ZhangCollege of Life Science, Shandong Normal University, Jinan 250100, China.

Qun LiuCollege of Life Science, Shandong Normal University, Jinan 250100, China.

Jingjuan LiShandong Key Laboratory of Bulk Open-Field Vegetable Breeding, Ministry of Agriculture and Rural Affairs Key Laboratory of Huang Huai Protected Horticulture Engineering, Institute of Vegetables, Shandong Academy of Agricultural Sciences, Jinan 250100, China.

Yihui ZhangShandong Key Laboratory of Bulk Open-Field Vegetable Breeding, Ministry of Agriculture and Rural Affairs Key Laboratory of Huang Huai Protected Horticulture Engineering, Institute of Vegetables, Shandong Academy of Agricultural Sciences, Jinan 250100, China.

Lixia WangShandong Key Laboratory of Bulk Open-Field Vegetable Breeding, Ministry of Agriculture and Rural Affairs Key Laboratory of Huang Huai Protected Horticulture Engineering, Institute of Vegetables, Shandong Academy of Agricultural Sciences, Jinan 250100, China.ORCID 0000-0001-7760-699X

Jianwei GaoShandong Key Laboratory of Bulk Open-Field Vegetable Breeding, Ministry of Agriculture and Rural Affairs Key Laboratory of Huang Huai Protected Horticulture Engineering, Institute of Vegetables, Shandong Academy of Agricultural Sciences, Jinan 250100, China.

Funding

the 2022 Tai 'an Agricultural Superior Seed Project 2022NYLZ07the "333" Talent Project of Shandong Academy of Agricultural Sciences CXGC2025F07the Agricultural Science and Technology Innovation Project of Shandong Academy of Agricultural Sciences CXGC2025C08the China Agriculture Research System CARS-23-G13the Key R&D Program of Shandong Province 2023LZGC014the Key R&D Program of Shandong Province 2024KJHZ005the Key R&D Program of Shandong Province 2024LZGC03602the National Natural Science Foundation, China 32172591the Project of 20 New Items for Universities in Jinan, Shandong 202228058the Shandong Agriculture Research System, China SDARS-05

6 · The paper itself

Abstract

Leaf morphogenesis is governed by a tightly integrated regulatory network centered on auxin, which operates through a sequential axis of synthesis, transport, and signal transduction. This review elucidates how pivotal molecular hubs previously identified in this regulatory network, including biosynthetic enzymes, polar transporters, and auxin response factors, interconnect through dynamic feedback mechanisms to orchestrate leaf initiation, polarity establishment, and the determination of its final size and shape. Notably, recent breakthroughs are transforming the field: the re-evaluation of established pathways like indole-3-acetaldoxime (IAOx), whose direct contribution to auxin pools is under scrutiny, hinting at the existence of undiscovered enzymes or alternative metabolic branches and the paradigm-shifting discovery that cAMP functions as a second messenger produced by Transport Inhibitor Resistant 1/Auxin signaling F-box (TIR1/AFB) receptors, which directly activates

Indexed as

auxinbiosynthesisleaf morphogenesissignalingtransport

Identifiers

PMID41515016

DOI10.3390/plants15010072

PMCPMC12787603

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.