Evidence map›Paper›PMID 41515249›Full record

SynthesisNutrients2025

Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.

Shooka Mohammadi, Damoon Ashtary-Larky, Mahsa Erfanian-Salim, Navid Alaghemand, Mojtaba Yousefi, Pouyan Sanjari Pirayvatlou, Mohammadreza Mirkarimi, Sara Ayazian Mavi, Ilnaz Alavi, Yeganeh Ettehad and 4 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shooka MohammadiDepartment of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0001-9157-1922
Damoon Ashtary-LarkyNutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.ORCID 0000-0001-7968-6110
Mahsa Erfanian-SalimDepartment of Pediatric Cardiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran 1416753955, Iran.
Navid AlaghemandNutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.
Mojtaba YousefiDepartment of Cardiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.
Pouyan Sanjari PirayvatlouDepartment of Internal Medicine, Faculty of Medicine, Alborz University of Medical Sciences, Karaj 3149969415, Iran.
Mohammadreza MirkarimiDepartment of Pediatrics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.
Sara Ayazian MaviDepartment of Community Medicine, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.
Ilnaz AlaviDivision of Cardiovascular Medicine, School of Medicine, University of Louisville, Louisville, KY 40222, USA.ORCID 0000-0002-2894-5757
Yeganeh EttehadDepartment of Internal Medicine, Faculty of Medicine, Alborz University of Medical Sciences, Karaj 3149969415, Iran.ORCID 0009-0004-5777-7782
Milad MehrbodDepartment of Internal Medicine, Mercy San Juan Medical Center, Carmichael, CA 95608, USA.ORCID 0009-0005-7995-6068
Omid AsbaghiCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1985717443, Iran.
Katsuhiko SuzukiFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0000-0002-6572-5809
Russel J ReiterDepartment of Cell Systems and Anatomy, Long School of Medicine, UT Health San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0001-6763-4225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiometabolic Risk FactorsCardiovascular DiseasesDietary SupplementsMelatoninAntioxidantsBlood GlucoseBlood PressureC-Reactive ProteinDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicAntioxidantsBlood GlucoseC-Reactive ProteinMelatoninblood pressurecardiometabolic risksglycemic controlinflammationlipid profilemelatoninoxidative stress

Identifiers

PMID41515249
PMCPMC12787795

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.