Evidence map›Paper›PMID 41515383›Full record

ReviewMolecules (Basel, Switzerland)2025

Magnetic Microrobots for Drug Delivery: A Review of Fabrication Materials, Structure Designs and Drug Delivery Strategies.

Jin Shi, Yanfang Li, Dingran Dong, Junyang Li, Tao Wen, Yue Tang, Qi Zhang, Fei Pan, Liqi Yan, Duanpo Wu and 1 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jin ShiSchool of Automation, Hangzhou Dianzi University, Qiantang District, Hangzhou 310020, China.
Yanfang LiSchool of Communication Engineering, Hangzhou Dianzi University, Qiantang District, Hangzhou 310020, China.ORCID 0000-0002-3165-0941
Dingran DongSchool of Computer Science, Hangzhou Dianzi University, Qiantang District, Hangzhou 310020, China.
Junyang LiDepartment of Electronic Engineering, Ocean University of China, Qingdao 266100, China.
Tao WenNorth Automatic Control Technology Institute, Taiyuan 030006, China.
Yue TangSchool of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0001-9912-4289
Qi ZhangDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong SAR 999077, China.
Fei PanSchool of Interdisciplinary Studies, Lingnan University, Tuen Mun, New Territories, Hong Kong SAR 999077, China.
Liqi YanSchool of Computer Science, Hangzhou Dianzi University, Qiantang District, Hangzhou 310020, China.
Duanpo WuSchool of Communication Engineering, Hangzhou Dianzi University, Qiantang District, Hangzhou 310020, China.
Shaowei JiangSchool of Communication Engineering, Hangzhou Dianzi University, Qiantang District, Hangzhou 310020, China.

Funding

Fundamental Research Funds for the Provincial Universities of Zhejiang GK259909299001-307Research project of Hangzhou Dianzi University KYS085625301
6 · The paper itself

Abstract

Magnetic microrobots have emerged as a promising platform for drug delivery in recent years. By enabling remotely controlled motion and precise navigation under external magnetic fields, these systems offer new solutions to overcome the limitations of traditional drug delivery nanocarriers, such as inadequate tissue penetration and heterogeneous biodistribution. Over the past few years, significant advancements have been made in the structural design of magnetic microrobots, as well as in drug loading techniques and stimuli-responsive drug release mechanisms, thereby demonstrating distinct advantages in enhancing therapeutic efficacy and targeting precision. This review provides a comprehensive overview of magnetic drug delivery microrobots, which are categorised into biomimetic structural, bio-templated and advanced material-based types, and introduces their differences in propulsion efficiency and biocompatibility. Additionally, drug loading and release strategies are summarised, including physical adsorption, covalent coupling, encapsulation, and multistimuli-responsive mechanisms such as pH, enzyme activity and thermal triggers. Overall, these advancements highlight the significant potential of magnetic microrobots in targeted drug delivery and emphasise the key challenges in their clinical translation, such as biological safety, large-scale production and precise targeted navigation within complex biological environments.

Indexed as

Drug Delivery SystemsMagneticsRoboticsAnimalsDrug CarriersDrug LiberationHumansDrug Carriersdrug deliverydrug loadingdrug releasemagnetic microrobots

Identifiers

PMID41515383
PMCPMC12787128

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.