Evidence map›Paper›PMID 41515450›Full record

ReviewMolecules (Basel, Switzerland)2026

Key Dietary Flavonoids: Insights into Their Structural Characteristics, Antioxidant and Anti-Inflammatory Activities, and Potential as Neuroprotective Agents.

Mirtha Navarro-Hoyos, Rajesh Bisoyi, Puja Kc, Nicholas Lutz, Mary Ruxsarash

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Inclusion of Supercritical Fluid Extract ofAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Neuroprotective effects ofBiomedical reports · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mirtha Navarro-HoyosChemistry Department, Georgetown University, Washington, DC 20057, USA.ORCID 0000-0003-2115-4677
Rajesh BisoyiChemistry Department, Georgetown University, Washington, DC 20057, USA.ORCID 0009-0006-5494-4631
Puja KcChemistry Department, Georgetown University, Washington, DC 20057, USA.ORCID 0000-0003-3385-5796
Nicholas LutzChemistry Department, Georgetown University, Washington, DC 20057, USA.ORCID 0009-0006-9435-4302
Mary RuxsarashChemistry Department, Georgetown University, Washington, DC 20057, USA.ORCID 0009-0005-6410-5682

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among natural products, polyphenols have drawn special attention due to their antioxidant properties and inherent anti-inflammatory mechanisms. Within polyphenols, flavonoids are particularly important because of their availability in natural sources and promising research results in both in vitro and in vivo studies. The wide range of potential health benefits associated with these molecules has led to an increase in consumption, both as ingredients and extracts, in dietary supplements. Four types of flavonoids that have experienced significant attention are flavonols, flavones, anthocyanins, and flavan-3-ols, including proanthocyanidins. The increasing consumer awareness of the cognitive health benefits associated with the antioxidant and anti-inflammatory properties of these flavonoids has led to a rise in demand for these molecules in products that promote healthy aging. This review aims to provide an overview of these four types of flavonoids, focusing on their structure, antioxidant role, anti-inflammatory properties and potential neuroprotective effects, addressing key health priorities for consumers.

Indexed as

Anti-Inflammatory AgentsAntioxidantsFlavonoidsNeuroprotective AgentsAnimalsAnthocyaninsDietary SupplementsHumansAnthocyaninsAnti-Inflammatory AgentsAntioxidantsFlavonoidsNeuroprotective Agentsanthocyaninsanti-inflammatory effectsantioxidant activityflavan-3-olsflavonesflavonoidsflavonolsneuroprotectionproanthocyanidins

Identifiers

PMID41515450
PMCPMC12787654

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.