Evidence map›Paper›PMID 41515939›Full record

ArticleInternational journal of molecular sciences2025

Integrated Assessment of the Cardiotoxic and Neurobehavioral Effects of 3,4-Methylenedioxypyrovalerone (MDPV) in Zebrafish Embryos.

Ouwais Aljabasini, Niki Tagkalidou, Juliette Bedrossiantz, Eva Prats, Raul Lopez-Arnau, Demetrio Raldua

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ouwais AljabasiniInstitute for Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0009-0002-8226-276X
Niki TagkalidouInstitute for Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0009-0004-3942-1432
Juliette BedrossiantzInstitute for Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0000-0001-6318-6453
Eva PratsResearch and Development Center (CID-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0000-0001-7838-2027
Raul Lopez-ArnauDepartment of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Pharmacology Section, Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-8904-7398
Demetrio RalduaInstitute for Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0000-0001-5256-1641

Funding

Ministerio de Ciencia, Innovación y Universidades PID2022-137541OB-I00Ministerio de Ciencia, Innovación y Universidades PID2023-148502OB-C21Ministerio de Ciencia, Innovación y Universidades PREP2022-104748Ministerio de Ciencia, Innovación y Universidades PREP2023-001814Plan Nacional sobre Drogas 2024I057
6 · The paper itself

Abstract

Synthetic cathinones such as 3,4-methylenedioxypyrovalerone (MDPV) are potent psychostimulants with high abuse potential, yet their systemic toxicity and neurobehavioral effects remain poorly characterized during early development. Using

Indexed as

CardiotoxicityCentral Nervous System StimulantsHeartLocomotionSynthetic CathinoneAnimalsAtrioventricular BlockEmbryo, NonmammalianToxicity TestsZebrafishCentral Nervous System StimulantsSynthetic Cathinonecardiotoxicitydopaminergic signalinggene expressionlocomotor activityMDPVprepulse inhibitionsynthetic cathinoneszebrafish embryos

Identifiers

PMID41515939
PMCPMC12785441

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.