Evidence mapPaperPMID 41515949Full record

ReviewInternational journal of molecular sciences2025

Neurovascular Signaling at the Gliovascular Interface: From Flow Regulation to Cognitive Energy Coupling.

Stefan Oprea, Cosmin Pantu, Daniel Costea, Adrian Vasile Dumitru, Catalina-Ioana Tataru, Nicolaie Dobrin, Mugurel Petrinel Radoi, Octavian Munteanu, Alexandru Breazu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefan OpreaFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0004-6296-8364
Cosmin PantuFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0004-9043-3690
Daniel CosteaPuls Med Association, 051885 Bucharest, Romania.
Adrian Vasile DumitruFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Catalina-Ioana TataruFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Nicolaie DobrinPuls Med Association, 051885 Bucharest, Romania.
Mugurel Petrinel RadoiFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Octavian MunteanuFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Alexandru BreazuFaculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thought processes in the brain occur as it continually modifies its use of energy. This review integrates research findings from molecular neurology, vascular physiology and non-equilibrium thermodynamics to create a comprehensive perspective on thinking as a coordinated energy process. Data shows that there is a relationship between the processing of information and metabolism throughout all scales, from the mitochondria's electron transport chain to the rhythmic changes in the microvasculature. Through the cellular level of organization, mitochondrial networks, calcium (Ca

Indexed as

BrainCognitionEnergy MetabolismNeurovascular CouplingAnimalsHumansMitochondriaThermodynamicsadaptive coherencebrain energeticsenergy-information couplingentropy minimizationgliovascular couplingmetabolic learningmitochondrial networkspredictive codingredox plasticitythermodynamic criticality

Identifiers

PMID41515949
PMCPMC12785549

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.