Evidence map›Paper›PMID 41516005›Full record

ArticleInternational journal of molecular sciences2025

Daisuke Uta, Takuya Yamane, Sosuke Yoneda, Erika Kasai, Toshiaki Kume

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daisuke UtaDepartment of Applied Pharmacology, Faculty of Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Toyama, Japan.ORCID 0000-0001-5644-1348
Takuya YamaneDepartment of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Toyama, Japan.ORCID 0000-0003-2426-7343
Sosuke YonedaNeuroscience, Drug Discovery & Disease Research Laboratory, Shionogi & Co., Ltd., Toyonaka 561-0825, Osaka, Japan.
Erika KasaiNeuroscience, Drug Discovery & Disease Research Laboratory, Shionogi & Co., Ltd., Toyonaka 561-0825, Osaka, Japan.
Toshiaki KumeDepartment of Applied Pharmacology, Faculty of Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Toyama, Japan.ORCID 0000-0003-2684-3666

Funding

Drug Discovery and Disease Research Laboratory, Shionogi & Co., Ltd. No numberJSPS KAKENHI 22K09020 and 19K09323
6 · The paper itself

Abstract

Neuropathic pain represents a critical challenge in medical research and clinical practice. Enhanced peripheral nerve activity and spinal dorsal horn neuronal firing are thought to contribute to the nociceptive hypersensitivities that are observed in chronic pain conditions, including those modeled by partial sciatic nerve ligation (PSNL). However, the detailed

Indexed as

Ganglia, SpinalNeuralgiaNeuronsSciatic NerveSpinal CordAnimalsDisease Models, AnimalExtracellular Signal-Regulated MAP KinasesHyperalgesiaLigationMalePhosphorylationPosterior Horn CellsRatsRats, Sprague-DawleyExtracellular Signal-Regulated MAP Kinasesdorsal root ganglionin vivo extracellular recordingsneuropathic painpartial sciatic nerve ligationspinal cord

Identifiers

PMID41516005
PMCPMC12785450

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.