Evidence mapPaperPMID 41516015Full record

ReviewInternational journal of molecular sciences2025

Decoding Breast Cancer: Emerging Molecular Biomarkers and Novel Therapeutic Targets for Precision Medicine.

Dámaris P Intriago-Baldeón, Eduarda Sofía Pérez-Coral, Martina Isabella Armas Samaniego, Vanessa I Romero, Juan Carlos Pozo Palacios, Gabriele Davide Bigoni-Ordóñez

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dámaris P Intriago-BaldeónGrupo de Investigación en Biomedicina Experimental y Aplicada, Facultad de Ciencias de la Salud, Universidad Internacional SEK (UISEK), Quito 170120, Ecuador.ORCID 0000-0001-9157-3979
Eduarda Sofía Pérez-CoralGrupo de Investigación en Biomedicina Experimental y Aplicada, Facultad de Ciencias de la Salud, Universidad Internacional SEK (UISEK), Quito 170120, Ecuador.ORCID 0009-0001-3677-3844
Martina Isabella Armas SamaniegoEscuela de Medicina, Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Quito 170901, Ecuador.ORCID 0009-0004-4435-2478
Vanessa I RomeroEscuela de Medicina, Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Quito 170901, Ecuador.ORCID 0000-0003-3048-9081
Juan Carlos Pozo PalaciosFacultad de Ciencias Médicas Eugenio Espejo, Campus Cuenca, Universidad UTE, Cuenca 010109, Ecuador.ORCID 0000-0002-2774-1787
Gabriele Davide Bigoni-OrdóñezCarrera de Laboratorio Clínico, Facultad de Ciencias Médicas, Universidad de Cuenca, Cuenca 010107, Ecuador.ORCID 0000-0003-2091-6107

Funding

University of Cuenca; Pontificia Universidad Católica del Ecuador No number
6 · The paper itself

Abstract

Breast cancer is the most frequent gynecological malignancy and the main cause of cancer death in the female population worldwide. One of the most significant challenges in its clinical management is the molecular heterogeneity of malignant breast tumors, which is reflected in the current molecular classification of these entities. In each of these tumor molecular subtypes, distinct genetic alterations are involved, and several intracellular signaling pathways contribute to defining their biological identity and clinical response. This literature review summarized the main classic and emerging biomarkers in breast cancer, along with the therapies associated with them. There are several classic biomarkers associated with this disease, such as estrogen and progesterone receptors, the HER2 receptor, and the Ki-67 cell proliferation marker. Given the limitations of these biomarkers, new biomarkers have been identified, including the

Indexed as

Biomarkers, TumorBreast NeoplasmsPrecision MedicineFemaleHumansMolecular Targeted TherapyBiomarkers, Tumorbreast cancermolecular biomarkersmolecular subtypesprecision medicinetherapeutic targets

Identifiers

PMID41516015
PMCPMC12785907

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.