Evidence map›Paper›PMID 41516037›Full record

ReviewInternational journal of molecular sciences2025

Understanding Fascial Tissue on the Molecular Level-How Its Unique Properties Enable Adaptation or Dysfunction.

Karen B Kirkness, Suzanne Scarlata

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karen B KirknessHealth Professions Education Unit, Hull York Medical School, York YO10 5DD, UK.ORCID 0000-0002-1649-7221
Suzanne ScarlataDepartment of Chemistry and Biochemistry, Worcester Polytechnic Institute, Worcester, MA 01609, USA.ORCID 0000-0001-5652-7467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite extensive research on fascial mechanobiology, no unified mechanotransduction framework has been established to explain how mechanical forces translate into adaptive cellular responses in fascial tissue. This narrative review synthesizes evidence from mesenchymal cell and fibroblast research to propose the Ca

Indexed as

Adaptation, PhysiologicalFasciaMechanotransduction, CellularAnimalsCalciumFibroblastsHumansHyaluronan ReceptorsHyaluronic AcidStress, MechanicalCalciumHyaluronan ReceptorsHyaluronic Acidcalcium signalingCD44extracellular matrixfasciafasciacytesHAS2hyaluronic acidmechanotransductionmorphogenetic fieldtissue adaptation

Identifiers

PMID41516037
PMCPMC12785924

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.