Evidence mapPaperPMID 41516154Full record

ArticleInternational journal of molecular sciences2025

Real-World Utility of GWAS-Based Diabetes Mellitus Panel Testing.

In Hwa Jeong, Kyung-Won Hong, Ja-Eun Choi, Bo-Kyung Shine

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

In Hwa JeongDepartment of Laboratory Medicine, Dong-A University College of Medicine, Dong-A University Hospital, Busan 49201, Republic of Korea.ORCID 0000-0001-8383-8228
Kyung-Won HongTheragen Health Co., Ltd., Seongnam 13488, Republic of Korea.ORCID 0000-0002-3137-4609
Ja-Eun ChoiTheragen Health Co., Ltd., Seongnam 13488, Republic of Korea.ORCID 0000-0002-4949-6348
Bo-Kyung ShineDepartment of Family Medicine, Dong-A University College of Medicine, Dong-A University Hospital, Busan 49201, Republic of Korea.ORCID 0000-0002-9160-2781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the clinical utility of a polygenic risk score (PRS)-based multigene panel test for predicting diabetes mellitus (DM) in a healthy population. A total of 302 individuals underwent genetic testing using the HelloGene™ DM panel, which includes four DM-related single nucleotide polymorphisms (

Indexed as

Diabetes Mellitus, Type 2Genome-Wide Association StudyAdultBlood GlucoseFemaleGenetic Predisposition to DiseaseGenetic Risk ScoreGenetic TestingGlycated HemoglobinHomeodomain ProteinsHumansKCNQ1 Potassium ChannelMaleMiddle AgedPolymorphism, Single NucleotideRepublic of KoreaBlood GlucoseCDKAL1 protein, humanGlycated HemoglobinHHEX protein, humanHomeodomain ProteinsKCNQ1 Potassium ChannelKCNQ1 protein, humanTCF7L2 protein, humanTranscription Factor 7-Like 2 ProteinTranscription FactorstRNA MethyltransferasesCDKAL1genome-wide association studyHHEXKCNQ1Polygenic risk scoreReal-world evidenceTCF7L2Type 2 diabetes mellitus

Identifiers

PMID41516154
PMCPMC12785355

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.