Evidence map›Paper›PMID 41516203›Full record

ArticleInternational journal of molecular sciences2025

Alterations of Apolipoprotein A1, E, and J Genes in the Frontal Cortex in an Ischemic Model of Alzheimer's Disease with 2-Year Survival.

Ryszard Pluta, Marzena Ułamek-Kozioł, Janusz Kocki, Anna Bogucka-Kocka, Jacek Bogucki, Stanisław J Czuczwar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. International journal of molecular sciences · 2026
    Article
  2. Genomic and proteomic conversion of brain ischemia to Alzheimer's disease.Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryszard PlutaDepartment of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0003-0764-1356
Marzena Ułamek-KoziołDepartment of Neurology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland.
Janusz KockiDepartment of Clinical Genetics, Medical University of Lublin, 20-080 Lublin, Poland.
Anna Bogucka-KockaDepartment of Biology and Genetics, Medical University of Lublin, 20-093 Lublin, Poland.
Jacek BoguckiFaculty of Medicine, John Paul II Catholic University of Lublin, 20-708 Lublin, Poland.ORCID 0000-0002-8683-545X
Stanisław J CzuczwarDepartment of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0003-2879-9945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article, we present genetic studies of apolipoproteins associated with Alzheimer's disease in the frontal cortex after ischemia and discuss their involvement in the development of neurodegeneration. Gene expression was assessed using an RT-PCR protocol at 2, 7, and 30 days and at 6, 12, 18, and 24 months after an episode of 10 min total cerebral ischemia.

Indexed as

Alzheimer DiseaseApolipoprotein A-IApolipoproteins EBrain IschemiaClusterinFrontal LobeAnimalsDisease Models, AnimalGene Expression RegulationHumansMaleApolipoprotein A-IApolipoproteins EClusterinAlzheimer’s diseaseapolipoprotein A1apolipoprotein Eapolipoprotein Jbrain ischemiaclusterinfrontal cortexgenes

Identifiers

PMID41516203
PMCPMC12785275

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.