Evidence mapPaperPMID 41516320Full record

ArticleInternational journal of molecular sciences2025

Modulation of Behavioral, Biochemical, Immunomodulatory, and Transcriptional Profiles by the Strain

Diana A Reznikova, Olga B Bekker, Alla V Stavrovskaya, Dmitry N Voronkov, Andrei A Gerasimov, Anastasiia K Pavlova, Ivan A Potapov, Mikhail V Ivanov, Veronika S Letvinova, Maya V Odorskaya and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Diana A ReznikovaLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0009-0003-3725-8101
Olga B BekkerLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0003-2015-0025
Alla V StavrovskayaRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.
Dmitry N VoronkovRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.ORCID 0000-0001-5222-5322
Andrei A GerasimovRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.
Anastasiia K PavlovaRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.
Ivan A PotapovRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.
Mikhail V IvanovRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.ORCID 0000-0001-5947-9093
Veronika S LetvinovaLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.
Maya V OdorskayaLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0002-9821-9865
Dilara A MavletovaLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0002-5852-7732
Aleksey A VatlinLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0002-6499-3908
Sergey N IllarioshkinRussian Center of Neurology and Neurosciences, 125367 Moscow, Russia.ORCID 0000-0002-2704-6282
Valery N DanilenkoLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0001-5780-0621

Funding

Grant of the Ministry of Science and Higher Education of the Russian Federation for the implementation of major scientific projects in priority areas of scientific and technological development 075-15-2024-638
6 · The paper itself

Abstract

Since there is currently no cure for Parkinson's disease, pharmacobiotic approaches based on gut microbiota-capable of producing pharmacologically active compounds-are under development. In this study, we propose LfU21, derived from the strain

Indexed as

Parkinson DiseaseTranscriptomeAcetylcysteinealpha-SynucleinAnimalsBehavior, AnimalBrain-Derived Neurotrophic FactorDisease Models, AnimalLipopolysaccharidesMaleRatsRats, WistarAcetylcysteinealpha-SynucleinBrain-Derived Neurotrophic FactorLipopolysaccharidescombined modellactacystinLimosilactobacillus fermentum U-21Parkinson’s diseasepharmacobiotic

Identifiers

PMID41516320
PMCPMC12786881

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.