Evidence map›Paper›PMID 41517968›Full record

ArticleJournal of labelled compounds & radiopharmaceuticals2026

Synthesis and Evaluation of Radioiodinated [

Chloe C McNamara, Agnes P Biju, Emma Lynn M Hipolito, Ngan T B Nguyen, Christopher Liang, Jogeshwar Mukherjee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of labelled compounds & radiopharmaceuticals, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Synthesis and Evaluation of Radioiodinated [Journal of labelled compounds & radiopharmaceuticals · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chloe C McNamaraPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, California, USA.
Agnes P BijuPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, California, USA.
Emma Lynn M HipolitoPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, California, USA.
Ngan T B NguyenPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, California, USA.
Christopher LiangPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, California, USA.
Jogeshwar MukherjeePreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, California, USA.ORCID https://orcid.org/0000-0003-1009-877X

Funding

Novel Tau-Targeted Radiohalogenated Agents for Alzheimer's DiseaseR01AG077700 · UNIVERSITY OF CALIFORNIA-IRVINE · 2025 to 2025
$698k
NIA NIH HHS R01 AG077700NIH HHS R01 AG077700
6 · The paper itself

Abstract

The aim of this study was to further understand the tau imaging agent, flortaucipir (T807), by making small modifications and assess its effect on tau protein binding in Alzheimer's disease (AD). Thus, the fluoropyridyl group in T807 was replaced with an iodine atom. We report here the development and preliminary evaluation of [

Indexed as

Alzheimer DiseaseBrainCarbolinesIodine RadioisotopesAutopsyChemistry Techniques, SyntheticHumanstau ProteinsCarbolinesIodine-125Iodine Radioisotopestau Proteins[125I]CTAU[18F]Flortaucipir[18F]T807Alzheimer's diseaseautoradiographyneurofibrillary tanglespostmortem human tau

Identifiers

PMID41517968
PMCPMC12789887

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.