ReviewJournal of biological engineering2026
Smart biomaterials for cardiovascular, bone, and skin tissue engineering: mechanisms, applications, and future prospects.
Review in Journal of biological engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Smart and stimuli-responsive hydrogels for controlled exosome delivery in bone tissue engineering: from passive carriers to intelligent therapeutic platforms.Cell and tissue banking · 2026Review
- 3D-printed core-shell scaffolds with a biphasic calcium phosphate core and GelMA hydrogel shell for bone tissue engineering.Scientific reports · 2026Article
- The cutting-edge advancements in biomaterials under the guidance of intelligence and bionics.Regenerative biomaterials · 2026Review
- Modeling and targeting the hostile physicochemical niche in bone metastasis: from experimental platforms to niche-directed therapy.Frontiers in cell and developmental biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smart biomaterials are engineered to dynamically respond to external stimuli, such as pH, temperature, light, and magnetic fields, enabling on-demand modifications in their physicochemical properties. The limited regenerative capacity of tissues and organs has driven the development of advanced materials that can actively guide cell behavior and promote healing. This review summarizes recent advances in both natural and synthetic stimuli-responsive biomaterials, emphasizing their mechanisms of responsiveness and classification, including shape-memory polymers, smart metals, nanocomposites, and multifunctional nanoagents. Applications in bone, skin, and cardiovascular tissue engineering are critically discussed, highlighting their potential to enhance osteogenesis, wound healing, and myocardial repair. Furthermore, current challenges and future directions are presented, outlining strategies to improve biocompatibility, mechanical properties, and clinical translation. By bridging fundamental mechanisms and biomedical applications, stimuli-responsive biomaterials offer transformative opportunities to revolutionize regenerative medicine and personalized therapy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.