Evidence map›Paper›PMID 41520036›Full record

ArticleScientific reports2026

Kazal-type serine protease inhibitors from Arabidopsis thaliana and Toxoplasma gondii exhibit antimicrobial activity against plant pathogens.

Manuel A Sánchez, Karen N Strack, Luisa F Mendoza-Morales, Victor A Ramos-Duarte, Eliane Pérez Sanchidrian, Valeria A Sander, Laguía-Becher Melina, Fernando L Pieckenstain, Marina Clemente

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Manuel A SánchezLaboratorio de Molecular Farming y Vacunas-UB6, Instituto Tecnológico de Chascomús (INTECH), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional General San Martín (UNSAM), Chascomús, Buenos Aires, Argentina.
Karen N StrackLaboratorio de Molecular Farming y Vacunas-UB6, Instituto Tecnológico de Chascomús (INTECH), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional General San Martín (UNSAM), Chascomús, Buenos Aires, Argentina.
Luisa F Mendoza-MoralesEscuela de Bio y Nanotecnologías (EByN), Campus Miguelete, 25 de Mayo y Francia, San Martín, Buenos Aires, Argentina.
Victor A Ramos-DuarteLaboratorio de Molecular Farming y Vacunas-UB6, Instituto Tecnológico de Chascomús (INTECH), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional General San Martín (UNSAM), Chascomús, Buenos Aires, Argentina.
Eliane Pérez SanchidrianLaboratorio de Molecular Farming y Vacunas-UB6, Instituto Tecnológico de Chascomús (INTECH), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional General San Martín (UNSAM), Chascomús, Buenos Aires, Argentina.
Valeria A SanderEscuela de Bio y Nanotecnologías (EByN), Campus Miguelete, 25 de Mayo y Francia, San Martín, Buenos Aires, Argentina.
Laguía-Becher MelinaLaboratorio de Molecular Farming y Vacunas-UB6, Instituto Tecnológico de Chascomús (INTECH), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional General San Martín (UNSAM), Chascomús, Buenos Aires, Argentina.
Fernando L PieckenstainEscuela de Bio y Nanotecnologías (EByN), Campus Miguelete, 25 de Mayo y Francia, San Martín, Buenos Aires, Argentina.
Marina ClementeLaboratorio de Molecular Farming y Vacunas-UB6, Instituto Tecnológico de Chascomús (INTECH), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional General San Martín (UNSAM), Chascomús, Buenos Aires, Argentina. mclemente@intech.gov.ar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kazal-type serine protease inhibitors (KPIs) interfere with microbial proteases and have been associated with antimicrobial activity, yet their specific role in plant protection remains poorly understood. In this work, we evaluated the antimicrobial potential of recombinant Arabidopsis thaliana KPI (rAtKPI-1 T), recombinant Toxoplasma gondii KPI (rTgPI-1), and two truncated versions of rTgPI-1 (rTgPI-1

Indexed as

Anti-Infective AgentsArabidopsisArabidopsis ProteinsSerine Proteinase InhibitorsToxoplasmaMicrobial Sensitivity TestsPlant DiseasesPseudomonas syringaeRecombinant ProteinsAnti-Infective AgentsArabidopsis ProteinsRecombinant ProteinsSerine Proteinase InhibitorsAntimicrobial activityArabidopsis thalianaBotrytis cinereaKazal-type inhibitorsPseudomonas sp.Toxoplasma gondii

Identifiers

PMID41520036
PMCPMC12868885

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.