Evidence map›Paper›PMID 41520239›Full record

ArticleJournal of food science2026

Micronized Dispersible Ferric Pyrophosphate (MDFP) in Extruded Rice Desserts: High Iron Bioavailability and Good Sensory Acceptance by Children.

Danielle Cristine Mota Ferreira, Thomás Valente de Oliveira, Maria Eliza Castro Moreira, Mônica Ribeiro Pirozi, Hércia Stampini Duarte Martino, Eduardo Basílio de Oliveira

Abstract read
In one paragraph

Article in Journal of food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danielle Cristine Mota FerreiraDepartment of Food Technology, Federal University of Viçosa, Viçosa, MG, Brazil.
Thomás Valente de OliveiraFaculty of Chemical Engineering, Federal University of Uberlândia, Patos de Minas, MG, Brazil.
Maria Eliza Castro MoreiraFaculty of Chemical Engineering, Federal University of Uberlândia, Patos de Minas, MG, Brazil.
Mônica Ribeiro PiroziDepartment of Food Technology, Federal University of Viçosa, Viçosa, MG, Brazil.
Hércia Stampini Duarte MartinoDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, MG, Brazil.
Eduardo Basílio de OliveiraDepartment of Food Technology, Federal University of Viçosa, Viçosa, MG, Brazil.ORCID https://orcid.org/0000-0002-2329-2507

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency in children is a persistent global public health problem. This study evaluated the efficacy of an extruded rice matrix as a carrier for micronized dispersible ferric pyrophosphate (MDFP), aiming to increase iron bioavailability in traditional rice-based desserts formulated with cow's milk (CM) or soy soluble protein extract (SSPE). Four experimental diets were administered to the rats: (i) fortified with CM and MDFP incorporated into extruded rice; (ii) fortified with SSPE and MDFP incorporated into extruded rice; (iii) control with ferrous sulfate (AIN-93G); and (iv) a control with pure MDFP (AIN-93G). Both fortified groups showed significantly higher recovery of iron nutritional status (p < 0.05), demonstrating that the different liquid ingredients did not compromise iron bioavailability. Gene expression analyses of key iron metabolism proteins (DMT-1, DcytB, ferroportin, hephaestin, transferrin, and ferritin) confirmed that the extruded rice matrix increased the bioavailability of MDFP compared to the compound in its pure form (p < 0.05), possibly reducing aggregation and favoring direct interaction with intestinal absorption sites. Furthermore, the fortified formulations demonstrated satisfactory sensory acceptance among school-ageRd children. These results indicate that incorporating MDFP into an extruded rice is an effective and technologically viable strategy for developing fortified rice desserts, with potential application in programs to combat iron deficiency anemia, specially in schoo-laged children at poor regions worldwide. PRACTICAL APPLICATIONS: Rice desserts fortified with micronized ferric pyrophosphate (MDFP) in an extruded rice matrix effectively improved iron availability without diminish sensory acceptance by children. Hence, the technology here reported offers a practical, low-cost strategy for school feeding programs as well as for food industry to develop fortified products to fight against iron deficiency anemia.

Indexed as

DiphosphatesFood, FortifiedIronIron, DietaryOryzaAnemia, Iron-DeficiencyAnimalsBiological AvailabilityCattleFerrous CompoundsFood, ProcessedHumansMaleMilkRatsDiphosphatesferric pyrophosphateFerrous Compoundsferrous sulfateIronIron, Dietary

Identifiers

PMID41520239
PMCPMC12790682

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.