ArticleScientific reports2026
Towards the transformation of MATLAB models into FPGA-Based hardware accelerators.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study presents a layer-wise, verification-oriented methodology for transferring computational models developed in MATLAB to Field-Programmable Gate Array (FPGA)–based hardware accelerators while preserving functional equivalence in a quantitatively verifiable manner. Existing MATLAB-to-FPGA conversion tools primarily focus on synthesis and resource optimization. In contrast, the proposed approach introduces a validated workflow that explicitly ensures layer-wise numerical consistency between software and hardware implementations. At each stage of the MATLAB–C++–FPGA workflow, golden output based verification is performed by comparing layer activations from a high-level synthesis (HLS)–based C + + model and the hardware implementation against reference outputs obtained in MATLAB. Layer-level accuracy is evaluated using the mean absolute error (MAE) metric, with all layers achieving MAE values below 1.5 × 10⁻³ when comparing MATLAB floating-point (FP) reference outputs with the HLS-based C + + model. Hardware validation is conducted on the Python Productivity for Zynq (PYNQ)-Z1 FPGA board. The convolutional layers are executed on the programmable logic (PL) using fixed-point arithmetic, while softmax and verification computations are performed on the processing system (PS) using FP arithmetic. This design maintains an end-to-end data flow from FP to fixed-point on the PL and back to FP, ensuring numerical accuracy and traceability across computational domains. The results demonstrate that the proposed method provides a reproducible verification framework for one-dimensional (1D) convolutional neural network (CNN)–based models and complements performance-oriented FPGA acceleration workflows by introducing a quantitatively traceable accuracy-preservation mechanism.
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