Evidence map›Paper›PMID 41521424›Full record

ArticleOncoimmunology2026

DNA prime and peptide boost immunization elicits robust neoantigen-specific CD8

Pablo Morgado-Cáceres, Francisca Hofmann-Vega, Diego Figueroa, Juan Saavedra-Almarza, Felipe Gálvez-Cancino, Ximena Díaz, Evelyn Menares, Eduardo Roa, Sofia Hidalgo, Manuel Varas-Godoy and 2 more

Abstract read
In one paragraph

Article in Oncoimmunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pablo Morgado-CáceresCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Francisca Hofmann-VegaCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Diego FigueroaCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Juan Saavedra-AlmarzaCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Felipe Gálvez-CancinoLaboratory of Immune-Regulation, NDM Centre for Immuno-Oncology, University of Oxford, Oxford, UK.
Ximena DíazCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Evelyn MenaresCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Eduardo RoaCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Sofia HidalgoCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Manuel Varas-GodoyCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Vincenzo BorgnaCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.
Alvaro LladserCentro BASAL Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.ORCID 0000-0002-5576-1478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic immunization against tumor neoantigens has the potential to induce potent and highly selective CD8

Indexed as

Antigens, NeoplasmCancer VaccinesCD8-Positive T-LymphocytesMelanoma, ExperimentalVaccines, DNAAnimalsCell Line, TumorDisease Models, AnimalFemaleImmunizationImmunization, SecondaryMiceMice, Inbred C57BLPeptidesProtein Subunit VaccinesAntigens, NeoplasmCancer VaccinesPeptidesProtein Subunit VaccinesVaccines, DNACD8+ T cellsDNA vaccineneoantigenpeptide vaccinetherapeutic vaccinestumor

Identifiers

PMID41521424
PMCPMC12802984

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.