ArticleQuantitative imaging in medicine and surgery2026
Echocardiography-derived pulmonary vascular resistance outperforms coagulation profiles and thromboelastography in predicting in-hospital mortality among surgical intensive care unit patients.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Patients in the surgical intensive care unit (SICU) frequently present with coagulation disorders and cardiopulmonary interaction disturbances. This study aimed to examine alterations in coagulation status and pulmonary vascular resistance (PVR), and compare their predictive efficacy for in-hospital mortality in this population. Methods: In this prospective observational study (January 2025 to April 2025), 61 consecutive SICU patients were enrolled and stratified into survivors (n=43) and non-survivors (n=18). Comprehensive echocardiographic assessments were performed to quantify PVR. Coagulation test and thromboelastography (TEG) were used to monitor coagulation status. Multivariable logistic regression identified independent predictors of in-hospital mortality. Results: Non-survivors exhibited marked prolonged activated partial thromboplastin time (APTT) [33.20 (30.50-39.30) Conclusions: Among SICU patients, echocardiography-derived PVR demonstrates superior clinical utility over coagulation tests and TEG in predicting in-hospital mortality among SICU patients, highlighting the prognostic significance of PVR and the combined model incorporating PVR, APTT, and FDP in critical illness outcomes.
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