Evidence mapPaperPMID 41522165Full record

ReviewJournal of thoracic disease2025

A narrative review of electrocardiogram manifestation of myocardial infarction with non-obstructive coronary arteries (MINOCA).

Arshdeep Raul, Shyla Gupta, Annie Hung, Hasan Alturki, Amin Meghdadi, Sebastian Garcia-Zamora, Sanoj Chacko, Norberto Bornancini, Martha Gulati, Adrian Baranchuk

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arshdeep Raul *Division of Cardiology, Queen's University, Kingston, ON, Canada.ORCID https://orcid.org/0009-0004-8431-6711
Shyla Gupta *Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID https://orcid.org/0000-0001-5568-5148
Annie HungDivision of Cardiology, Queen's University, Kingston, ON, Canada.ORCID https://orcid.org/0009-0002-2146-1028
Hasan AlturkiDivision of Cardiology, Queen's University, Kingston, ON, Canada.ORCID https://orcid.org/0009-0000-0582-2570
Amin MeghdadiDivision of Cardiology, Queen's University, Kingston, ON, Canada.ORCID https://orcid.org/0009-0000-6322-3162
Sebastian Garcia-ZamoraDepartment of the Coronary Care Unit, Delta Clinic, Rosario, Argentina.ORCID https://orcid.org/0000-0001-6846-0247
Sanoj ChackoDivision of Cardiology, Queen's University, Kingston, ON, Canada.ORCID https://orcid.org/0000-0003-1699-6247
Norberto BornanciniDepartment of Cardiology, Sanatorio Santa Clara Talar, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-2777-4570
Martha GulatiDepartment of Cardiology, Barbra Streisand Women' s Heart Center, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-0735-9756
Adrian BaranchukDivision of Cardiology, Queen's University, Kingston, ON, Canada.ORCID https://orcid.org/0000-0002-3042-6569

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Myocardial infarction with non-obstructive coronary arteries (MINOCA) represents a unique subset of acute coronary syndromes where significant coronary artery obstruction is absent. Despite its clinical relevance, the role of electrocardiogram (ECG) in the diagnosis of MINOCA remains underexplored, with no specific guidelines established. This review examines the current literature to elucidate potential diagnostic markers and guide clinical management. Methods: A non-systematic review was conducted using the PubMed database, focusing on literature from 2015 onwards, involving studies that analyze the ECGs of patients with MINOCA. Additional data from two representative MINOCA cases at Kingston Health Sciences Centre were also reviewed to illustrate real-world ECG variability and diagnostic value. Key Content and Findings: ST-segment elevations are observed in 5-10.5% of MINOCA cases and studies performed on women found ST-segment depression in 15% of cases, T-wave inversions in 45% of cases, prolonged QTc intervals in 28% of cases and 35% present with a normal initial ECG. Conclusions: Recognizing these diverse ECG presentations of MINOCA is crucial for tailoring management strategies to the underlying pathology, thereby minimizing both over-treatment and under-treatment. Future studies should prioritize longitudinal tracking of ECG changes and correlations with outcomes to establish standardized diagnostic criteria and improve prognostic stratification. This review highlights the significance of conducting additional research to develop clear ECG guidelines tailored specifically for MINOCA.

Indexed as

Acute coronary syndrome (ACS)electrocardiogram (ECG)myocardial infarction with non-obstructive coronary arteries (MINOCA)ST-segment depressionST-segment elevation

Identifiers

PMID41522165
PMCPMC12780395

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.