Evidence map›Paper›PMID 41522176›Full record

ArticleJournal of thoracic disease2025

Quality of life and survival of achieving textbook outcome for resectable esophageal squamous cell carcinoma.

Xinming Nie, Kaixin Zhao, Qin Xie, Wenwu He, Simiao Lu, Chenghao Wang, Yan Miao, Longlin Jiang, Kangning Wang, Guangyuan Liu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xinming Nie *Clinical Medical College, Southwest Medical University, Luzhou, China.
Kaixin Zhao *Clinical Medical College, Southwest Medical University, Luzhou, China.
Qin Xie *Department of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Wenwu HeDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Simiao LuDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Chenghao WangDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Yan MiaoDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Longlin JiangDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Kangning WangDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Guangyuan LiuDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Qiang FangDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Lin PengDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Xuefeng Leng *Department of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Yongtao Han *Clinical Medical College, Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between textbook outcome (TO) and health-related quality of life (QOL) is unclear. Our purpose is to investigate the relationship between achieving TO and survival and postoperative QOL in individuals with esophageal squamous cell carcinoma (ESCC). Methods: We conducted analyses of consecutive patients with ESCC who underwent minimally invasive McKeown esophagectomy in a single center from April 2019 to December 2020. The patients were grouped into a TO group and a non-TO group. The longitudinal QOL was handled using a linear mixed effect model. The European Organization for Research and Treatment of Cancer (EORTC) questionnaires were used to assess symptoms and QOL. Results: One hundred and twenty-three patients (33.3%) achieved TO. Postoperative complications and insufficient lymph node dissection were the main reasons that hindered achieving TO. In the EORTC Quality of Life Questionnaire Core-30 (EORTC QLQ-C30) and EORTC Quality of Life Esophagus-specific Questionnaire (EORTC QLQ-S18) scales, compared to the non-TO group, the TO group reported worse social function, more financial impact, less trouble with taste, milder dysphagia and better disease-free survival (DFS) and overall survival (OS). Conclusions: Patients who could achieve the TO might experience a milder dysphagia symptom, better DFS and OS in the short term after esophagectomy. The postoperative management of the patients who can achieve the TO should be strengthened to improve the postoperative QOL.

Indexed as

esophageal canceresophagectomypatient-reported outcomesquality of life (QOL)Textbook outcome (TO)

Identifiers

PMID41522176
PMCPMC12780393

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.