ReviewAutophagy reports2026
Glycophagy: molecular mechanisms, regulatory signals, and disease associations.
Review in Autophagy reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Contradictory Effects on Hepatocytes in ASMD.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glycophagy is a process of selective degradation of glycogen through the autophagy pathway. It relies on key proteins, such as STBD1 (glycogen-specific autophagy receptor), GABARAPL1 (member of the ATG8 family), and acid α-glucosidase (GAA), and proceeds through the steps of "glycogen recognition - autophagosome encapsulation - lysosomal degradation" to release glucose, thereby maintaining energy homeostasis. This process is regulated by multiple signaling pathways, such as AMPK, mTOR, CAMP/PKA, and calcium signaling pathways, which jointly respond to cellular energy demands and metabolic states. Glycophagy occurs under conditions, such as starvation, exercise, and energy metabolism disorders, and plays a role in diseases with glycogen metabolism disorders. Its functions include energy supply, blood sugar regulation, maintenance of cellular homeostasis, and influencing cellular aging. Dysfunction of glycophagy can lead to various diseases, such as glycogen storage diseases and diabetic cardiomyopathy. In-depth study of the regulatory mechanisms of glycophagy is helpful for developing therapeutic strategies for related diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.