Evidence mapPaperPMID 41522771Full record

ArticleDEN open2026

Efficacy and Safety of a Revised Gastric Peroral Endoscopic Myo-Neurotomy Procedure for Bariatric Endoscopy in a Porcine Model.

Yasushi Yamasaki, Kenta Hamada, Junki Toyosawa, Akinobu Takaki, Takehiro Tanaka, Hiroyuki Okada, Motoyuki Otsuka

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasushi YamasakiDepartment of Gastroenterology Okayama University Hospital Okayama Japan.ORCID https://orcid.org/0000-0002-2992-9863
Kenta HamadaDepartment of Gastroenterology Okayama University Hospital Okayama Japan.
Junki ToyosawaDepartment of Gastroenterology Okayama University Hospital Okayama Japan.ORCID https://orcid.org/0000-0002-4640-6730
Akinobu TakakiDepartment of Gastroenterology Okayama University Hospital Okayama Japan.
Takehiro TanakaDepartment of Pathology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama Japan.
Hiroyuki OkadaDepartment of Gastroenterology Okayama University Hospital Okayama Japan.
Motoyuki OtsukaDepartment of Gastroenterology Okayama University Hospital Okayama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endoscopic sleeve gastroplasty is a minimally invasive and effective treatment for obesity, although gastric mucosa folding and subsequent reduced visibility of the gastric lining raise concerns for some patients. This study evaluates the safety and efficacy of a revised peroral endoscopic myo-neurotomy (R-POEM-N) technique using a submucosal approach as an alternative bariatric procedure in a porcine model. Methods: Twelve pigs underwent either an R-POEM-N procedure ( Results: R-POEM-N was successfully completed in all pigs without significant adverse events. The procedure time was 171.3 ± 3.0 min. The proportional change in body weight was significantly lower in the R-POEM-N group compared with the control group ( Conclusions: R-POEM-N successfully reduced weight gain in pigs, supporting its potential as a novel bariatric intervention with minimal invasiveness.

Indexed as

bariatric endoscopybody weightinterventionobesityperoral endoscopic myo‐neurotomy

Identifiers

PMID41522771
PMCPMC12788173

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.