Evidence map›Paper›PMID 41523097›Full record

ArticleBio-protocol2026

FLARE: A Flow Cytometry-Based Fluorescent Assay for Measuring HSV-1 Nuclear Egress.

Bing Dai, Lucas Polack, Samantha Moores, Ariana C Calderon-Zavala, Ekaterina E Heldwein

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bing DaiDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA.
Lucas PolackDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA.
Samantha MooresGraduate Program in Genetics, Molecular, and Cellular Biology, Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA, USA.
Ariana C Calderon-ZavalaDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA.
Ekaterina E HeldweinDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA.

Funding

Mechanisms of nuclear egress in herpesvirusesR01AI192496 · NIAID · TUFTS UNIVERSITY BOSTON · PI HELDWEIN, EKATERINA · 2025 to 2025
$3.3M
Biophysical and structural analysis of the herpesviral nuclear budding machineryR01AI147625 · NIAID · TUFTS UNIVERSITY BOSTON · PI HELDWEIN, EKATERINA · 2019 to 2023
$3.0M
Spectral Cell SorterS10OD032201 · OD · TUFTS UNIVERSITY BOSTON · PI TAI, ALBERT K · 2022 to 2022
$672k
NIAID NIH HHS R01 AI147625NIAID NIH HHS R01 AI192496NIH HHS S10 OD032201
6 · The paper itself

Abstract

During herpesvirus replication, capsids are assembled inside the nucleus and translocated into the cytosol by a non-canonical nucleocytoplasmic export process termed

Indexed as

AntibodyCapsidDouble fluorescent reporter systemFlow cytometryFluorescence reporterHSV-1Nuclear egressNucleocytoplasmic export

Identifiers

PMID41523097
PMCPMC12782854

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.