ArticleRespirology case reports2026
Marked Reversibility of Functional Small Airway Disease Following Reduction of Hazardous Inhalational Exposure: A PRM CT Case Report.
Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Identification of imaging-based pulmonary and extrapulmonary treatable traits in COPD: a review.Frontiers in medicine · 2026Review
- Marked Reversibility of Functional Small Airway Disease Following Reduction of Hazardous Inhalational Exposure: A PRM CT Case Report.Respirology case reports · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case illustrating the role of parametric response mapping (PRM) in detecting and monitoring small airway disease (SAD) related to occupational inhalational exposure. A 52-year-old woman, a lifelong never-smoker with chronic occupational exposure to metal cutting-fluid fumes and metal particles, presented with exertional dyspnea and moderate airflow obstruction. PRM CT revealed PRM-functional small airway disease (PRM-fSAD) of 15.7% and PRM-emphysema of 0.2%. After 1.5 years of increased unprotected exposure, PRM-fSAD rose to 46.2%, with stable spirometry but reduced diffusing capacity and more frequent exacerbations. Following workload reduction and consistent mask use, PRM-fSAD decreased to 2.8% accompanied by symptomatic and functional improvement. This case supports PRM as a reliable imaging biomarker for early detection of exposure-related SAD, even before spirometric decline, and highlights the potential reversibility of occupational lung injury with timely intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.