Evidence map›Paper›PMID 41523232›Full record

ReviewCardiac failure review2025

Phrenic Nerve Stimulation for Central Sleep Apnoea: When and Why?

Jonathan Na, Miguel Valderrabano, Paul Schurmann

Abstract readReview
In one paragraph

Review in Cardiac failure review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan NaDivision of Cardiac Electrophysiology, Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital Houston, TX, US.ORCID https://orcid.org/0000-0002-5061-7493
Miguel ValderrabanoDivision of Cardiac Electrophysiology, Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital Houston, TX, US.ORCID https://orcid.org/0000-0002-8401-1684
Paul SchurmannDivision of Cardiac Electrophysiology, Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital Houston, TX, US.ORCID https://orcid.org/0000-0002-6855-8014

Funding

VENOUS ETHANOL ABLATION IN ISCHEMIC VENTRICULAR TACHYCARDIA- VELVET TRIALR33HL164873 · NHLBI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI Miguel Valderrabano · 2024 to 2026
$2.1M
NHLBI NIH HHS R33 HL164873
6 · The paper itself

Abstract

Central sleep apnoea (CSA) is a sleep-disordered breathing condition characterised by diminished or absent respiratory effort during sleep due to instability in the respiratory control system. While various treatments exist, ranging from positive airway pressure therapy to pharmacological interventions, many patients' symptoms remain refractory to standard therapies. Phrenic nerve stimulation, particularly through devices such as the remedē System, represents a novel, evidence-based therapeutic avenue for patients with moderate to severe CSA. This review provides a comprehensive overview of CSA, explores the underlying pathophysiology, evaluates conventional treatments, and examines the mechanisms, efficacy and limitations of phrenic nerve stimulation based on current literature.

Indexed as

atrial fibrillationcentral sleep apnoeaheart failurePhrenic nerve stimulation

Identifiers

PMID41523232
PMCPMC12784273

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.