ReviewCureus2025
Pregnancy After Bariatric Surgery: Hepatobiliary Implications, Maternal Outcomes, and Clinical Considerations.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global rise in bariatric surgery among women of reproductive age has led to an increasing number of pregnancies occurring after significant metabolic and anatomical changes. While bariatric surgery improves fertility and metabolic health, its long-term impact on hepatobiliary physiology during pregnancy remains incompletely understood. This narrative review explores the hepatobiliary implications of pregnancy following bariatric surgery, summarizes maternal and fetal outcomes, and highlights clinical considerations for multidisciplinary management. A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted for studies published between 2000 and 2025, using the terms "bariatric surgery," "pregnancy," "liver function," "gallstones," "cholestasis," and "maternal outcomes." Relevant clinical studies, reviews, and case reports were analyzed and synthesized narratively. Animal studies, non-English-language articles, and studies without pregnancy or hepatobiliary outcomes were excluded from analysis. Pregnancy after bariatric surgery is associated with improved metabolic and obstetric profiles compared with pregnancies in untreated obesity. However, rapid weight loss and altered bile acid metabolism predispose patients to hepatobiliary complications, including gallstone formation, biliary colic, and nutritional liver dysfunction. Liver function test abnormalities are frequent but often transient. Early conception (<12 months post-surgery) increases the risk of micronutrient deficiencies and hepatocellular stress. Close monitoring, nutritional optimization, and coordinated care among obstetricians, surgeons, and hepatologists are essential. Pregnancy following bariatric surgery presents unique hepatobiliary challenges requiring individualized, multidisciplinary management. Further research is needed to elucidate the pathophysiologic mechanisms linking altered bile acid metabolism and hepatic adaptation in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.