Evidence map›Paper›PMID 41523692›Full record

ReviewFood science and biotechnology2026

The gut-bone axis: potential influence of anthocyanins and implications for postmenopausal osteoporosis.

Briana M Nosal, Alexander Aksenov, Catherine Andersen, Elaine Choung-Hee Lee, Yanjiao Zhou, Ock K Chun

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Food science and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Briana M NosalDepartment of Nutritional Sciences, University of Connecticut, 27 Manter Road, Unit 4017, Storrs, CT 06269 USA.
Alexander AksenovDepartment of Chemistry, University of Connecticut, Storrs, CT 06269 USA.
Catherine AndersenDepartment of Nutritional Sciences, University of Connecticut, 27 Manter Road, Unit 4017, Storrs, CT 06269 USA.
Elaine Choung-Hee LeeDepartment of Kinesiology, University of Connecticut, Storrs, CT 06269 USA.
Yanjiao ZhouDepartment of Medicine, University of Connecticut Health, Farmington, CT 06032 USA.
Ock K ChunDepartment of Nutritional Sciences, University of Connecticut, 27 Manter Road, Unit 4017, Storrs, CT 06269 USA.ORCID 0000-0002-7391-2380

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the aging population worldwide and increased life expectancy, the risk of postmenopausal osteoporosis (PMO) is an increased public health concern. Current treatments for PMO have declined in use over the past decade which has led to an increased focus on finding dietary agents that possess antioxidant and anti-inflammatory properties for prophylaxis and treatment of osteoporosis. Anthocyanins (ACNs) have been shown to exert therapeutic effects in chronic diseases due to their antioxidant and anti-inflammatory properties. ACNs are also thought to be involved in modulating the gut microbiome owing to their prebiotic properties. The gut microbiome has been implicated as a potential target for osteoporosis prevention and treatment since it can modulate immune and endocrine systems, which influence bone metabolism. This review summarizes findings related to ACNs' influence on the gut-bone axis, with a focus on the immune and endocrine systems and potential implications for PMO prevention.

Indexed as

AnthocyaninsEndocrine systemGut microbiomeImmune systemMenopauseOsteoporosis

Identifiers

PMID41523692
PMCPMC12789291

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.