Evidence map›Paper›PMID 41524571›Full record

ReviewJournal of experimental botany2026

The sucrose-trehalose 6-phosphate nexus: what's next for plant vigour and productivity?

Brian Ayre

Abstract readReview
In one paragraph

Review in Journal of experimental botany, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Brian AyreDepartment of Biological Sciences and BioDiscovery Institute, University of North Texas, Denton, TX 76201, USA.ORCID 0000-0002-7399-200X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sucrose-trehalose 6-phosphate nexus model states that trehalose 6-phosphate (Tre6P) is both a signal for sucrose (Suc) status and a negative feedback regulator that helps maintain Suc levels within an optimal range. The link between Suc and Tre6P is best established in Arabidopsis and other plants that transport primarily Suc, but angiosperms have evolved multiple phloem loading strategies and use alternative sugars. Annunziata et al. (2025) find conservation of the Suc-Tre6P nexus across angiosperms despite different sugars being transported, different mechanisms for phloem loading, and different photoassimilate storage strategies through day/night (diel) cycles. Tre6P as a universal signalling metabolite has implications for increasing crop vigour and productivity.

Indexed as

MagnoliopsidaSucroseSugar PhosphatesTrehaloseArabidopsisCrops, AgriculturalPhloemSucroseSugar PhosphatesTrehalosetrehalose-6-phosphateCarbon partitioningphloem transportsucrosetrehalose 6-phosphate

Identifiers

PMID41524571
PMCPMC12794207

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.