Evidence map›Paper›PMID 41524880›Full record

ArticleAnnals of surgical oncology2026

Alcohol Use Disorder versus Adverse In-Hospital Outcomes after Radical Cystectomy and Ileal Conduit Urinary Diversion.

Federico Polverino, Calogero Catanzaro, Michele Nicolazzini, Michele Petix, Leonardo Quarta, Maximilian Filzmayer, Jordan A Goyal, Simone Morra, Gianluigi Califano, Claudia Collà Ruvolo and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Federico PolverinoCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada. fedepolve97@gmail.com.ORCID http://orcid.org/0009-0007-6218-3761
Calogero CatanzaroCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Michele NicolazziniCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Michele PetixCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Leonardo QuartaCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Maximilian FilzmayerCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Jordan A GoyalCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Simone MorraCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Gianluigi CalifanoDepartment of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.
Claudia Collà RuvoloCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Roberto La RoccaDepartment of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.
Alberto BrigantiVita-Salute San Raffaele University, Milan, Italy.
Felix K H ChunDepartment of Urology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Carlotta PalumboDivision of Urology, Department of Translational Medicine, University of Eastern Piedmont, Maggiore della Carità Hospital, Novara, Italy.
Riccardo SchiavinaDivision of Urology, IRCCS Azienda Ospedaliero-universitaria di Bologna, Bologna, Italy.
Gennaro MusiDepartment of Urology, IEO European Institute of Oncology, IRCCS, Milan, Italy.
Shahrokh F ShariatDepartment of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Fred SaadCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Nicola LongoDepartment of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.
Pierre I KarakiewiczCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadical cystectomy (RC) is the gold standard treatment for muscle-invasive bladder cancer (BCa). Alcohol use disorder (AUD) may predispose to worse adverse in-hospital outcomes after RC and ileal conduit urinary diversion. The current study addressed this knowledge gap. PATIENTS AND

methodsDescriptive analyses, propensity score matching (PSM), and multivariable logistic and Poisson regression models were used to address patients with BCa treated with RC and ileal conduit within National Inpatient Sample (2006-2019).

resultsOf 15,018 RC and ileal conduit patients, 320 (2.1%) had history of AUD at baseline. Compared with their non-AUD counterparts, patients with AUD exhibited significantly higher rates of adverse in-hospital outcomes in 9 of 14 categories, namely: critical care therapies (Δ + 12.0%), overall complications (Δ + 11.0%), prolonged length of stay (Δ + 11.0%), pulmonary complications (Δ + 6.0%), acute kidney injury (Δ + 5.0%), hepatic complications (Δ + 3.2%), in-hospital mortality (Δ + 2.8%), cardiac complications (Δ + 1.6%), and total hospital charges (Δ + 7925 US$, all p < 0.05). After multivariable adjustment, AUD independently predicted higher rates of adverse in-hospital outcomes in the same 9 of 15 categories, namely: hepatic complications [odds ratio (OR) 3.3], in-hospital mortality (OR 3.2), acute kidney injury (OR 1.7), overall complications (OR 1.7), cardiac complications (OR 1.5), critical care therapies (OR 1.4), prolonged length of stay (OR 1.3), pulmonary complications (OR 1.2), and total hospital charges (OR 1.2, all p < 0.01).

conclusionsSince AUD significantly predisposes to higher rates of adverse in-hospital outcomes and in-hospital mortality after RC and ileal conduit urinary diversion, precautionary measures prior to admission and during hospital stay may be warranted in patients with AUD.

Indexed as

AlcoholismCystectomyPostoperative ComplicationsUrinary Bladder NeoplasmsUrinary DiversionAgedFemaleFollow-Up StudiesHospital MortalityHumansLength of StayMaleMiddle AgedPrognosisSurvival RateAlcohol use disorderComplicationsCystectomyNISUrinary bladder cancer

Identifiers

PMID41524880

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.