Evidence map›Paper›PMID 41526338›Full record

ArticleInternational journal of oral science2026

Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells.

Haoran Du, Qiong Li, Chenchen Zhou, Junji Xu, Kang Gao, Zixiao Li, Yifan Xu, Ousheng Liu, Bing Li, Jianguang Xu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of oral science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Haoran Du *Department of International Medical Center, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Qiong Li *Beijing Laboratory of Oral Health, Capital Medical University, Beijing, China.ORCID 0000-0003-4376-1224
Chenchen ZhouState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Diseases & Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.ORCID 0000-0002-6427-5869
Junji XuCollege of Stomatology, Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing Medical University, Chongqing, China.
Kang GaoDepartment of International Medical Center, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Zixiao LiDepartment of International Medical Center, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Yifan XuBeijing Laboratory of Oral Health, Capital Medical University, Beijing, China.
Ousheng LiuXiangya Stomatological Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0003-3293-9824
Bing LiSchool and Hospital of Stomatology, Shanxi Medical University, Taiyuan, Shanxi, China.
Jianguang XuCollege & Hospital of Stomatology, Key Laboratory of Oral Diseases Research of Anhui Province, Anhui Medical University, Hefei, Anhui, China.
Jingsong WangBeijing Laboratory of Oral Health, Capital Medical University, Beijing, China.
Hideaki KagamiDepartment of Dentistry and Oral and Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Xianqi LiDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Matsumoto Dental University, Shiojiri, Japan.
Su ChenDepartment of International Medical Center, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Jian ZhouDepartment of International Medical Center, Beijing Stomatological Hospital, Capital Medical University, Beijing, China. zhoujian@ccmu.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82170951National Natural Science Foundation of China (National Science Foundation of China) 82470961
6 · The paper itself

Abstract

The functional regeneration of the dentin-pulp complex is pivotal for tooth preservation, yet the molecular mechanisms governing odontoblast differentiation remain poorly understood. In the current study, we revealed a distinct NKD1

Indexed as

Dental PulpDentinogenesisMSX1 Transcription FactorOdontogenesisStem CellsWnt3A ProteinAnimalsCell DifferentiationHumansMiceOdontoblastsSwineMSX1 Transcription FactorWnt3A ProteinWnt3a protein, mouse

Identifiers

PMID41526338
PMCPMC12796365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.