Evidence map›Paper›PMID 41526346›Full record

ArticleNature communications2026

ERECTA genes and their ligands regulate shoot and inflorescence architecture in maize.

Xiao Liu, Jinbiao Wang, Jipeng Li, Lu Kang, Mengyan Wang, Zhaoyu Huang, Jarrett Man, Xuxu Huang, Zhiming Zhang, Fang Yang and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. ERECTA-family receptor kinases: versatile regulators of plant developmental signaling.The Plant journal : for cell and molecular biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiao Liu *The Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China.ORCID http://orcid.org/0009-0006-4155-9224
Jinbiao Wang *The Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China.ORCID http://orcid.org/0000-0002-1025-2995
Jipeng LiThe Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China.ORCID http://orcid.org/0000-0002-0985-5326
Lu KangSchool of Agriculture and Biotechnology, Sun Yat-Sen University, Shenzhen, China.
Mengyan WangThe Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China.ORCID http://orcid.org/0009-0000-1252-765X
Zhaoyu HuangThe Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China.ORCID http://orcid.org/0009-0006-1185-1021
Jarrett ManBiology Department, University of Massachusetts, Amherst, MA, USA.
Xuxu HuangThe Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China.
Zhiming ZhangState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, China.
Fang YangSchool of Agriculture and Biotechnology, Sun Yat-Sen University, Shenzhen, China.ORCID http://orcid.org/0000-0002-1915-8874
Madelaine BartlettSainsbury Laboratory, Cambridge University, 47 Bateman Street, Cambridge, CB2 1LR, UK.ORCID http://orcid.org/0000-0002-0369-8606
Liuji WuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.ORCID http://orcid.org/0000-0002-0653-2193
Zhaobin DongState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0002-1275-581X
David JacksonCold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA. jacksond@cshl.edu.ORCID http://orcid.org/0000-0002-4269-7649
Fang XuThe Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University, Qingdao, China. fxu@sdu.edu.cn.ORCID http://orcid.org/0000-0003-0767-1272

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32101741National Natural Science Foundation of China (National Science Foundation of China) U22A20460National Natural Science Foundation of China (National Science Foundation of China) U22A20474National Science Foundation (NSF) IOS-2131631Natural Science Foundation of Shandong Province (Shandong Provincial Natural Science Foundation) ZR2023JQ012
6 · The paper itself

Abstract

In maize, several yield-related traits are associated with meristem activity, regulated by CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptide signals perceived by CLAVATA(CLV) receptors in the CLAVATA-WUSCHEL (CLV-WUS) pathway. However, additional signaling pathways in maize meristem development remain poorly understood. Here, we identify three receptor-like kinases, ZmERECTA1 (ZmER1), ZmER2 and ZmER1-like (ZmERL), and their ligands, EPIDERMAL PATTERNING FACTOR-like (ZmEPFL), as critical regulators of meristem activity, plant architecture, and ear development. We demonstrate that ZmER receptors act redundantly, with ZmER1 playing a primary role. Zmer1 mutants have compact architecture, enlarged inflorescence meristems (IMs), and increased kernel row numbers (KRNs), while higher-order Zmer mutants display exacerbated phenotypes. We further reveal that ZmER1 specifically binds to five EPFL peptides, which act redundantly in ear development regulation. Furthermore, we find that ZmWUS1 is upregulated in Zmer mutants and mutation in Zmwus1 partially suppress the enlarged IM of Zmer1 mutants. We also generate weak Zmer1 alleles with enhanced yield traits, including reduced leaf angles and increased KRN. These findings offer valuable insights into ER-EPFL signaling in maize meristem development and provide promising genetic targets for breeding high-yield maize varieties through optimized plant and ear architecture.

Indexed as

InflorescencePlant ProteinsPlant ShootsProtein Serine-Threonine KinasesReceptors, Cell SurfaceZea maysGene Expression Regulation, PlantLigandsMeristemMutationPhenotypePlants, Genetically ModifiedSignal TransductionLigandsPlant ProteinsProtein Serine-Threonine KinasesReceptors, Cell Surface

Identifiers

PMID41526346
PMCPMC12795852

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.