Evidence map›Paper›PMID 41526370›Full record

ArticleNature communications2026

Binary mineral nanoparticles enable intravascular delivery of metal ions to tumors for metalloimmunotherapy.

Bao Loc Nguyen, Ngoc Duy Le, Thi Oanh Oanh Nguyen, Daehyeon Ahn, Basavaraj Rudragouda Patil, Beomsu Kim, Cao Dai Phung, Duc-Vinh Pham, Jung Min Lee, Jiwoo Hong and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Membrane-Coated Iron Oxide (FeInternational journal of nanomedicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bao Loc NguyenCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Ngoc Duy LeCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Thi Oanh Oanh NguyenCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.ORCID http://orcid.org/0009-0006-8398-3736
Daehyeon AhnSchool of Mechanical Engineering, Soongsil University, Seoul, Republic of Korea.
Basavaraj Rudragouda PatilCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.ORCID http://orcid.org/0000-0003-2683-8082
Beomsu KimCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Cao Dai PhungCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.ORCID http://orcid.org/0000-0001-5771-2664
Duc-Vinh PhamCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.ORCID http://orcid.org/0000-0002-3098-3541
Jung Min LeeSchool of Mechanical Engineering, Soongsil University, Seoul, Republic of Korea.
Jiwoo HongSchool of Mechanical Engineering, Soongsil University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-2226-597X
Jae-Hoon ChangCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.ORCID http://orcid.org/0000-0002-1001-6570
Sae Kwang KuCollege of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Jeonghwan KimCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea. jeonghwankim@yu.ac.kr.ORCID http://orcid.org/0000-0002-1697-5107
Jong Oh KimCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea. jongohkim@yu.ac.kr.ORCID http://orcid.org/0000-0002-4929-851X

Funding

National Research Foundation of Korea (NRF) RS-2022-NR070844National Research Foundation of Korea (NRF) RS-2024-00343765National Research Foundation of Korea (NRF) RS-2025-02303064National Research Foundation of Korea (NRF) RS-2025-14292970
6 · The paper itself

Abstract

Although disruptions in metal ion homeostasis leading to severe cellular damage and regulated cell death are a promising strategy for cancer immunotherapy, challenges in overloading these ions to tumor cells without premature release have limited their therapeutic applications. In this study, we develop binary mineral nanoparticles incorporating both Ca

Indexed as

ImmunotherapyMineralsNanoparticlesNeoplasmsAnimalsCalciumCell Line, TumorHumansHydrogen-Ion ConcentrationMiceSodiumCalciumMineralsSodium

Identifiers

PMID41526370
PMCPMC12895034

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.