Evidence map›Paper›PMID 41526387›Full record

ArticleNature communications2026

Cross-species dissection of saline-related genes by genetically deciphering a euryhaline microalga Chlorella sp.

Aoqi Wang, Qinhua Gan, Yi Xin, Ying Deng, Xiao Han, Yandu Lu

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aoqi Wang *Engineering and Research Center of Marine Bioactives & Bioproducts of Hainan Province, School of Marine Biology and Fisheries, Hainan University, Haikou, China.
Qinhua Gan *Engineering and Research Center of Marine Bioactives & Bioproducts of Hainan Province, School of Marine Biology and Fisheries, Hainan University, Haikou, China.
Yi Xin *Engineering and Research Center of Marine Bioactives & Bioproducts of Hainan Province, School of Marine Biology and Fisheries, Hainan University, Haikou, China.
Ying DengEngineering and Research Center of Marine Bioactives & Bioproducts of Hainan Province, School of Marine Biology and Fisheries, Hainan University, Haikou, China.
Xiao HanEngineering and Research Center of Marine Bioactives & Bioproducts of Hainan Province, School of Marine Biology and Fisheries, Hainan University, Haikou, China.
Yandu LuEngineering and Research Center of Marine Bioactives & Bioproducts of Hainan Province, School of Marine Biology and Fisheries, Hainan University, Haikou, China. ydlu@hainanu.edu.cn.ORCID http://orcid.org/0000-0002-0136-2252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deciphering adaptation to habitat shifts across the salinity boundary necessitates investigation of "lost" and "acquired" saline genes. By assembling a telomere-to-telomere genome, we propose that the euryhaline Chlorophyta Chlorella sp. MEM25 represents an early-diverging saltwater species that has evolved numerous genes essential for saltwater-freshwater transitions. By comparison with Viridiplantae genomes, we identify ancestral genes and lineage-specific genes related to salinity adaptation. Loss-of-function mutants of the proposed salt-sensitive genes in algae and plants exhibit increased salt resistance, highlighting the potential of the MEM25 genome as a breeding resource. Notably, the gene RMI1 plays an important role in salinity tolerance across species, from microalgae to higher plants.

Indexed as

ChlorellaMicroalgaeSalt TolerancePhylogenySalinity

Identifiers

PMID41526387
PMCPMC12902096

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.