ArticleBMC nephrology2026
Plant-based low-protein diet for preventing malnutrition‒inflammation complex syndrome in adults with CKD: a single-centre preliminary experience.
Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Knowledge, attitude, and practice toward medical nutritional therapy among patients with chronic kidney disease.Frontiers in nutrition · 2026Article
- Association between protein-energy wasting and cognitive impairment in maintenance hemodialysis patients.Frontiers in nutrition · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) is a rising public health concern. Low protein intake reduces uremic toxin generation and improves the hemodynamic profile of the kidneys, postponing the need for eventual dialysis. Vegetarian diets have been shown to positively influence cardiovascular health and reduce uremic toxin levels and inflammation in CKD patients. The so-called “Malnutrition-Inflammation Complex Syndrome” (MICS) is a nontraditional cardiovascular risk factor that is associated with poor overall outcomes in CKD patients. The type of protein, not only the amount, may be relevant in the prevention of MICS, but at present no studies are published in the literature addressing this topic. The aim of our study was to evaluate the feasibility and efficacy of a plant-based diet in reducing CKD-related complications and preventing MICS.
methodsAdult subjects with CKD (3–5 stages) were retrospectively recruited. Each patient was evaluated for biochemical parameters, anthropometric measurements, body composition, and pharmacological treatments at baseline and after 6 months of dietary intervention.
resultsAfter six months of treatment, significant improvements (p < 0.05) were observed in indices of kidney function, lipid and glycemic profiles, vitamin D levels, plasma fibrinogen, anthropometric and body composition parameters, as well as muscle strength, whereas no significant changes were detected in plasma albumin levels or in the other parameters assessed. As observed in recent literature, the risk of hyperkalaemia associated with plant-based regimens in CKD patients has been set aside.
conclusionsOur preliminary study confirms the feasibility and efficacy of a plant-based diet in reducing CKD-related complications and preventing MICS.
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Registered trials
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