Evidence map›Paper›PMID 41527009›Full record

SynthesisJournal of health, population, and nutrition2026

Association between dietary habits and risk of functional dyspepsia: a systematic review and meta-analysis of observational data.

Negar Ostadsharif, Fahimeh Haghighatdoost, Mohammad Amoushahi Forooshani, Parisa Hajihashemi, Peyman Adibi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of health, population, and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Negar OstadsharifStudent Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Fahimeh HaghighatdoostIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad Amoushahi ForooshaniStudent Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Parisa HajihashemiNutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. hashemi.p@res.mui.ac.ir.
Peyman AdibiIsfahan Gastroenterology and Hepatology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDietary habits may influence functional dyspepsia (FD), but their role remains inconclusive and unclear. These inconsistencies highlight the need for further research to establish evidence-based dietary guidelines. This systematic review and meta-analysis aimed to assess the link between dietary habits and FD, and their potential as modifiable factors in FD management.

designIn this systematic review and meta-analysis, a comprehensive search was conducted up to December 2025.

settingStudies were identified in PubMed, ISI Web of Science, and Scopus.

participantsWe included observational studies involving adults with FD that investigated the association between various dietary habits and FD.

resultsAfter screening 2,640 articles, we identified 11 studies comprising 21,220 participants. The meta-analysis revealed that spicy food consumption significantly increased the risk of FD by 32% (n = 4, OR = 1.32, 95% CI: 1.04-1.67), as well as epigastric pain (n = 4, OR = 1.46, 95% CI: 1.22-1.75) and epigastric burning (n = 4, OR = 1.47, 95% CI: 1.21-1.78). Additionally, higher meal frequency was associated with a reduced risk of FD (n = 2, OR = 0.52, 95% CI: 0.32-0.86). There was no significant association between spicy food consumption and early satiety or postprandial fullness.

conclusionThis study indicated that spicy food consumption might be associated with an increased risk of FD, epigastric pain, and burning. However, higher meal frequency might have protective effect on FD. Further high-quality studies are warranted to confirm these results.

Indexed as

DietDyspepsiaFeeding BehaviorHumansObservational Studies as TopicRisk FactorsDietary habitsFunctional dyspepsiaGastrointestinal disordersSpicy foods

Identifiers

PMID41527009
PMCPMC12888455

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.