ArticleJournal of feline medicine and surgery2026
Diagnosis of pyogranulomatous and neutrophilic lymphadenitis in 72 cats presenting to a referral hospital: with a focus on nine cats with steroid-responsive lymphadenitis.
Article in Journal of feline medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectivesThe aim of the study was to review diagnoses and infectious disease testing of cats with neutrophilic or pyogranulomatous lymphadenitis, and describe the history, clinicopathological abnormalities, diagnostic imaging findings, lymph node cytological/histological appearance, treatment response and outcome of steroid-responsive lymphadenitis in cats.MethodsThe medical records of 72 cats documented to have pyogranulomatous, neutrophilic or mixed lymphadenitis between January 2015 and December 2023 at a single referral hospital were retrospectively reviewed.ResultsFeline infectious peritonitis (25/72, 35%) was the most common cause of lymphadenitis and frequently pyogranulomatous. Neoplasia (11/72, 15%) was the overall next most common cause and the most common cause of neutrophilic lymphadenitis. The remaining diagnoses included nine (12.5%) cats with steroid-responsive lymphadenitis, eight (11%) with inflammatory disease, seven (10%) with other suspected bacterial infections, five (7%) with mycobacterial infections, five (7%) with neutrophilic to pyogranulomatous lymphadenitis of unclear cause and two (3%) with toxoplasmosis with variable inflammatory lymphadenitis. Steroid-responsive lymphadenitis cases were often middle-aged (median 7 years 10 months) castrated males (6/9). Common signs included lethargy (7/9, 78%), hyporexia/anorexia (7/9, 78%), pyrexia (7/9, 78%), peripheral lymphadenopathy (6/9) and weight loss (5/9). Frequently affected lymph nodes were submandibular (5/9), popliteal (4/9) and jejunal (4/9). Cytology was more commonly neutrophilic (8/14, 57%) than pyogranulomatous (4/14, 29%). After variable infectious disease testing, all cats received prednisolone (median dose 1.25 mg/kg, range 0.5-2.3) for a median of 5.75 months (range 4-11). All improved initially; relapse occurred in 33% during treatment, after tapering or discontinuation. Two cats (22%) were euthanased after relapse, with one developing neurological signs.Conclusions and relevanceSteroid-responsive lymphadenitis should be considered in cats presenting with inflammatory lymphadenopathy when no identifiable underlying infectious, inflammatory or neoplastic cause is identified, and most cases respond well to glucocorticoid treatment.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.